Molecular basis for disassembly of an importin:ribosomal protein complex by the escortin Tsr2

Ribosomal proteins are transported to the nucleus with the help of importins, from which they are released prior to incorporation into the nascent ribosome. Here the authors report the NMR structure of the ribosomal protein eS26 in complex with the escortin Tsr2 and shed light on the mechanism of eS...

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Autores principales:	Sabina Schütz, Erich Michel, Fred F. Damberger, Michaela Oplová, Cohue Peña, Alexander Leitner, Ruedi Aebersold, Frederic H.-T. Allain, Vikram Govind Panse
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2018
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/6a9a3ed39ff54d0fae4c92979ac96f5c
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spelling	oai:doaj.org-article:6a9a3ed39ff54d0fae4c92979ac96f5c2021-12-02T15:34:36ZMolecular basis for disassembly of an importin:ribosomal protein complex by the escortin Tsr210.1038/s41467-018-06160-x2041-1723https://doaj.org/article/6a9a3ed39ff54d0fae4c92979ac96f5c2018-09-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-06160-xhttps://doaj.org/toc/2041-1723Ribosomal proteins are transported to the nucleus with the help of importins, from which they are released prior to incorporation into the nascent ribosome. Here the authors report the NMR structure of the ribosomal protein eS26 in complex with the escortin Tsr2 and shed light on the mechanism of eS26 release from importin.Sabina SchützErich MichelFred F. DambergerMichaela OplováCohue PeñaAlexander LeitnerRuedi AebersoldFrederic H.-T. AllainVikram Govind PanseNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-14 (2018)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Sabina Schütz Erich Michel Fred F. Damberger Michaela Oplová Cohue Peña Alexander Leitner Ruedi Aebersold Frederic H.-T. Allain Vikram Govind Panse Molecular basis for disassembly of an importin:ribosomal protein complex by the escortin Tsr2
description	Ribosomal proteins are transported to the nucleus with the help of importins, from which they are released prior to incorporation into the nascent ribosome. Here the authors report the NMR structure of the ribosomal protein eS26 in complex with the escortin Tsr2 and shed light on the mechanism of eS26 release from importin.
format	article
author	Sabina Schütz Erich Michel Fred F. Damberger Michaela Oplová Cohue Peña Alexander Leitner Ruedi Aebersold Frederic H.-T. Allain Vikram Govind Panse
author_facet	Sabina Schütz Erich Michel Fred F. Damberger Michaela Oplová Cohue Peña Alexander Leitner Ruedi Aebersold Frederic H.-T. Allain Vikram Govind Panse
author_sort	Sabina Schütz
title	Molecular basis for disassembly of an importin:ribosomal protein complex by the escortin Tsr2
title_short	Molecular basis for disassembly of an importin:ribosomal protein complex by the escortin Tsr2
title_full	Molecular basis for disassembly of an importin:ribosomal protein complex by the escortin Tsr2
title_fullStr	Molecular basis for disassembly of an importin:ribosomal protein complex by the escortin Tsr2
title_full_unstemmed	Molecular basis for disassembly of an importin:ribosomal protein complex by the escortin Tsr2
title_sort	molecular basis for disassembly of an importin:ribosomal protein complex by the escortin tsr2
publisher	Nature Portfolio
publishDate	2018
url	https://doaj.org/article/6a9a3ed39ff54d0fae4c92979ac96f5c
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Molecular basis for disassembly of an importin:ribosomal protein complex by the escortin Tsr2

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