Structure of the initiation-competent RNA polymerase I and its implication for transcription

Structure of the initiation-competent RNA polymerase I and its implication for transcription

Eukaryotic RNA polymerase I (Pol I) is responsible for the transcription of rRNA genes. Here the authors determine the cryo-EM structure of the Pol I-Rrn3 complex, providing insight into how Rrn3 stabilizes the monomeric initiation competent Pol I to drive pre-initiation complex formation.

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Autores principales: Michael Pilsl, Corinne Crucifix, Gabor Papai, Ferdinand Krupp, Robert Steinbauer, Joachim Griesenbeck, Philipp Milkereit, Herbert Tschochner, Patrick Schultz
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2016
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Science
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Acceso en línea:https://doaj.org/article/6aa07fa9078d4b249ab94428a0822512
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