Inhibition of protein glycosylation is a novel pro-angiogenic strategy that acts via activation of stress pathways

Therapeutic angiogenesis has the potential of inducing and maintaining new blood vessels and thus improving outcomes in patients with ischemic disorders. Mannosamine functions as an endothelial cell mitogen/survival factor through activation of stress pathways and might be useful to protect and rege...

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Autores principales: Cuiling Zhong, Pin Li, Sulabha Argade, Lixian Liu, Anastasia Chilla’, Wei Liang, Hong Xin, Brian Eliceiri, Biswa Choudhury, Napoleone Ferrara
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2020
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Acceso en línea:https://doaj.org/article/6aabbcd93d4447ac8c52afeed98db825
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spelling oai:doaj.org-article:6aabbcd93d4447ac8c52afeed98db8252021-12-02T14:16:55ZInhibition of protein glycosylation is a novel pro-angiogenic strategy that acts via activation of stress pathways10.1038/s41467-020-20108-02041-1723https://doaj.org/article/6aabbcd93d4447ac8c52afeed98db8252020-12-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-20108-0https://doaj.org/toc/2041-1723Therapeutic angiogenesis has the potential of inducing and maintaining new blood vessels and thus improving outcomes in patients with ischemic disorders. Mannosamine functions as an endothelial cell mitogen/survival factor through activation of stress pathways and might be useful to protect and regenerate the vascular endothelium in a variety of disorders.Cuiling ZhongPin LiSulabha ArgadeLixian LiuAnastasia Chilla’Wei LiangHong XinBrian EliceiriBiswa ChoudhuryNapoleone FerraraNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-21 (2020)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Cuiling Zhong
Pin Li
Sulabha Argade
Lixian Liu
Anastasia Chilla’
Wei Liang
Hong Xin
Brian Eliceiri
Biswa Choudhury
Napoleone Ferrara
Inhibition of protein glycosylation is a novel pro-angiogenic strategy that acts via activation of stress pathways
description Therapeutic angiogenesis has the potential of inducing and maintaining new blood vessels and thus improving outcomes in patients with ischemic disorders. Mannosamine functions as an endothelial cell mitogen/survival factor through activation of stress pathways and might be useful to protect and regenerate the vascular endothelium in a variety of disorders.
format article
author Cuiling Zhong
Pin Li
Sulabha Argade
Lixian Liu
Anastasia Chilla’
Wei Liang
Hong Xin
Brian Eliceiri
Biswa Choudhury
Napoleone Ferrara
author_facet Cuiling Zhong
Pin Li
Sulabha Argade
Lixian Liu
Anastasia Chilla’
Wei Liang
Hong Xin
Brian Eliceiri
Biswa Choudhury
Napoleone Ferrara
author_sort Cuiling Zhong
title Inhibition of protein glycosylation is a novel pro-angiogenic strategy that acts via activation of stress pathways
title_short Inhibition of protein glycosylation is a novel pro-angiogenic strategy that acts via activation of stress pathways
title_full Inhibition of protein glycosylation is a novel pro-angiogenic strategy that acts via activation of stress pathways
title_fullStr Inhibition of protein glycosylation is a novel pro-angiogenic strategy that acts via activation of stress pathways
title_full_unstemmed Inhibition of protein glycosylation is a novel pro-angiogenic strategy that acts via activation of stress pathways
title_sort inhibition of protein glycosylation is a novel pro-angiogenic strategy that acts via activation of stress pathways
publisher Nature Portfolio
publishDate 2020
url https://doaj.org/article/6aabbcd93d4447ac8c52afeed98db825
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