Characterisation of sterol biosynthesis and validation of 14α-demethylase as a drug target in Acanthamoeba

Characterisation of sterol biosynthesis and validation of 14α-demethylase as a drug target in Acanthamoeba

Abstract The soil amoebae Acanthamoeba causes Acanthamoeba keratitis, a severe sight-threatening infection of the eye and the almost universally fatal granulomatous amoebic encephalitis. More effective treatments are required. Sterol biosynthesis has been effectively targeted in numerous fungi using...

Descripción completa

Guardado en:
Detalles Bibliográficos
Autores principales: Scott Thomson, Christopher A. Rice, Tong Zhang, RuAngelie Edrada-Ebel, Fiona L. Henriquez, Craig W. Roberts
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2017
Materias:
Medicine
R
Science
Q
Acceso en línea:https://doaj.org/article/6aae8a6a857649b49c992ac7999b6f8f
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!

Ejemplares similares

Ejemplares similares