Work-related risk factors for ulnar nerve entrapment in the Northern Finland Birth Cohort of 1966

Abstract Ulnar nerve entrapment (UNE) is the second most common entrapment neuropathy in the upper extremity. The aetiology of UNE is multifactorial and is still not fully understood. The aim of the study was to identify occupational risk factors for UNE and to determine whether smoking modifies the...

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Autores principales:	Laura Miettinen, Jorma Ryhänen, Rahman Shiri, Jaro Karppinen, Jouko Miettunen, Juha Auvinen, Sina Hulkkonen
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Medicine R Science Q
Acceso en línea:	https://doaj.org/article/6abae4333b024daa8d1faea5b12865ab
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spelling	oai:doaj.org-article:6abae4333b024daa8d1faea5b12865ab2021-12-02T15:36:13ZWork-related risk factors for ulnar nerve entrapment in the Northern Finland Birth Cohort of 196610.1038/s41598-021-89577-72045-2322https://doaj.org/article/6abae4333b024daa8d1faea5b12865ab2021-05-01T00:00:00Zhttps://doi.org/10.1038/s41598-021-89577-7https://doaj.org/toc/2045-2322Abstract Ulnar nerve entrapment (UNE) is the second most common entrapment neuropathy in the upper extremity. The aetiology of UNE is multifactorial and is still not fully understood. The aim of the study was to identify occupational risk factors for UNE and to determine whether smoking modifies the effects of work-related factors on UNE. The study population consisted of the Northern Finland Birth Cohort of 1966 (NFBC1966). In total, 6325 individuals active in working life participated at baseline in 1997. Occupational risk factors were evaluated by a questionnaire at baseline. The data on hospitalizations due to UNE were obtained from the Care Register for Health Care between 1997 and 2018. The incidence rate of hospitalization due to UNE was 47.6 cases per 100,000 person-years. After adjusting for confounders, entrepreneurs (Hazard ratio (HR) = 3.68, 95% CI 1.20–11.27), smokers (HR = 2.51, 95% CI 1.43–4.41), workers exposed to temperature changes (HR = 1.72, 95% CI 1.00–2.93), workers with physically demanding jobs (HR = 3.02, 95% CI 1.39–6.58), and workers exposed to hand vibration (HR = 1.94, 95% CI 1.00–3.77) were at an increased risk of hospitalization for UNE. Exposure to work requiring arm elevation increased the risk of hospitalization due to UNE among smokers (HR = 2.62, 95% CI 1.13–6.07), but not among non-smokers. Work-related exposure to vibration and temperature changes, and physically demanding work increase the risk of hospitalization for UNE. Smoking may potentiate the adverse effects of work-related factors on UNE.Laura MiettinenJorma RyhänenRahman ShiriJaro KarppinenJouko MiettunenJuha AuvinenSina HulkkonenNature PortfolioarticleMedicineRScienceQENScientific Reports, Vol 11, Iss 1, Pp 1-9 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine R Science Q
spellingShingle	Medicine R Science Q Laura Miettinen Jorma Ryhänen Rahman Shiri Jaro Karppinen Jouko Miettunen Juha Auvinen Sina Hulkkonen Work-related risk factors for ulnar nerve entrapment in the Northern Finland Birth Cohort of 1966
description	Abstract Ulnar nerve entrapment (UNE) is the second most common entrapment neuropathy in the upper extremity. The aetiology of UNE is multifactorial and is still not fully understood. The aim of the study was to identify occupational risk factors for UNE and to determine whether smoking modifies the effects of work-related factors on UNE. The study population consisted of the Northern Finland Birth Cohort of 1966 (NFBC1966). In total, 6325 individuals active in working life participated at baseline in 1997. Occupational risk factors were evaluated by a questionnaire at baseline. The data on hospitalizations due to UNE were obtained from the Care Register for Health Care between 1997 and 2018. The incidence rate of hospitalization due to UNE was 47.6 cases per 100,000 person-years. After adjusting for confounders, entrepreneurs (Hazard ratio (HR) = 3.68, 95% CI 1.20–11.27), smokers (HR = 2.51, 95% CI 1.43–4.41), workers exposed to temperature changes (HR = 1.72, 95% CI 1.00–2.93), workers with physically demanding jobs (HR = 3.02, 95% CI 1.39–6.58), and workers exposed to hand vibration (HR = 1.94, 95% CI 1.00–3.77) were at an increased risk of hospitalization for UNE. Exposure to work requiring arm elevation increased the risk of hospitalization due to UNE among smokers (HR = 2.62, 95% CI 1.13–6.07), but not among non-smokers. Work-related exposure to vibration and temperature changes, and physically demanding work increase the risk of hospitalization for UNE. Smoking may potentiate the adverse effects of work-related factors on UNE.
format	article
author	Laura Miettinen Jorma Ryhänen Rahman Shiri Jaro Karppinen Jouko Miettunen Juha Auvinen Sina Hulkkonen
author_facet	Laura Miettinen Jorma Ryhänen Rahman Shiri Jaro Karppinen Jouko Miettunen Juha Auvinen Sina Hulkkonen
author_sort	Laura Miettinen
title	Work-related risk factors for ulnar nerve entrapment in the Northern Finland Birth Cohort of 1966
title_short	Work-related risk factors for ulnar nerve entrapment in the Northern Finland Birth Cohort of 1966
title_full	Work-related risk factors for ulnar nerve entrapment in the Northern Finland Birth Cohort of 1966
title_fullStr	Work-related risk factors for ulnar nerve entrapment in the Northern Finland Birth Cohort of 1966
title_full_unstemmed	Work-related risk factors for ulnar nerve entrapment in the Northern Finland Birth Cohort of 1966
title_sort	work-related risk factors for ulnar nerve entrapment in the northern finland birth cohort of 1966
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/6abae4333b024daa8d1faea5b12865ab
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Work-related risk factors for ulnar nerve entrapment in the Northern Finland Birth Cohort of 1966

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