Intracellular proton conductance of the hepatitis C virus p7 protein and its contribution to infectious virus production.

The hepatitis C virus (HCV) p7 protein is critical for virus production and an attractive antiviral target. p7 is an ion channel when reconstituted in artificial lipid bilayers, but channel function has not been demonstrated in vivo and it is unknown whether p7 channel activity plays a critical role...

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Autores principales: Ann L Wozniak, Stephen Griffin, David Rowlands, Mark Harris, MinKyung Yi, Stanley M Lemon, Steven A Weinman
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2010
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Acceso en línea:https://doaj.org/article/6ac03d00cdad48649ebc91dc982e3b13
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