Oleanolic acid induces apoptosis and autophagy via the PI3K/AKT/mTOR pathway in AGS human gastric cancer cells

Oleanolic acid induces apoptosis and autophagy via the PI3K/AKT/mTOR pathway in AGS human gastric cancer cells

Oleanolic acid (OA) is widely distributed in food and medicinal plants, it reportedly exerts anti-inflammatory and anti-cancer effects. In this study, we investigated the effect of OA on human gastric cancer cells AGS in vitro and in vivo. The OA treatment significantly inhibited the AGS cell viabil...

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Autores principales: Jae-Han Lee, Eun-Seon Yoo, So-Hee Han, Gi-Hwan Jung, Eun-Ji Han, Soo-Hyun Jung, Bum Seok Kim, Sung-Dae Cho, Jeong-Seok Nam, Changsun Choi, Jeong-Hwan Che, Ji-Youn Jung
Formato: article
Lenguaje:EN
Publicado: Elsevier 2021
Materias:
Oleanolic acid
Apoptosis
Autophagy
PI3K/AKT/mTOR pathway
Gastric cancer
Nutrition. Foods and food supply
TX341-641
Acceso en línea:https://doaj.org/article/6ac0df86965b49d8ab429c4b7b0e3e0f
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https://doaj.org/article/6ac0df86965b49d8ab429c4b7b0e3e0f

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