MICU1 controls cristae junction and spatially anchors mitochondrial Ca2+ uniporter complex

Proper mitochondrial structure is critical for normal function. Here, the authors show with SIM that the mitochondrial Ca2+ uniporter complex and localization of component MICU1 is critical to maintaining cristae junction stability and overall mitochondrial membrane structure.

Guardado en:

Detalles Bibliográficos
Autores principales:	Benjamin Gottschalk, Christiane Klec, Gerd Leitinger, Eva Bernhart, René Rost, Helmut Bischof, Corina T. Madreiter-Sokolowski, Snježana Radulović, Emrah Eroglu, Wolfgang Sattler, Markus Waldeck-Weiermair, Roland Malli, Wolfgang F. Graier
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2019
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/6ac9bbcf957c4a56ad8f56403898e532
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:6ac9bbcf957c4a56ad8f56403898e532
record_format	dspace
spelling	oai:doaj.org-article:6ac9bbcf957c4a56ad8f56403898e5322021-12-02T14:38:39ZMICU1 controls cristae junction and spatially anchors mitochondrial Ca2+ uniporter complex10.1038/s41467-019-11692-x2041-1723https://doaj.org/article/6ac9bbcf957c4a56ad8f56403898e5322019-08-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-11692-xhttps://doaj.org/toc/2041-1723Proper mitochondrial structure is critical for normal function. Here, the authors show with SIM that the mitochondrial Ca2+ uniporter complex and localization of component MICU1 is critical to maintaining cristae junction stability and overall mitochondrial membrane structure.Benjamin GottschalkChristiane KlecGerd LeitingerEva BernhartRené RostHelmut BischofCorina T. Madreiter-SokolowskiSnježana RadulovićEmrah ErogluWolfgang SattlerMarkus Waldeck-WeiermairRoland MalliWolfgang F. GraierNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-17 (2019)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Benjamin Gottschalk Christiane Klec Gerd Leitinger Eva Bernhart René Rost Helmut Bischof Corina T. Madreiter-Sokolowski Snježana Radulović Emrah Eroglu Wolfgang Sattler Markus Waldeck-Weiermair Roland Malli Wolfgang F. Graier MICU1 controls cristae junction and spatially anchors mitochondrial Ca2+ uniporter complex
description	Proper mitochondrial structure is critical for normal function. Here, the authors show with SIM that the mitochondrial Ca2+ uniporter complex and localization of component MICU1 is critical to maintaining cristae junction stability and overall mitochondrial membrane structure.
format	article
author	Benjamin Gottschalk Christiane Klec Gerd Leitinger Eva Bernhart René Rost Helmut Bischof Corina T. Madreiter-Sokolowski Snježana Radulović Emrah Eroglu Wolfgang Sattler Markus Waldeck-Weiermair Roland Malli Wolfgang F. Graier
author_facet	Benjamin Gottschalk Christiane Klec Gerd Leitinger Eva Bernhart René Rost Helmut Bischof Corina T. Madreiter-Sokolowski Snježana Radulović Emrah Eroglu Wolfgang Sattler Markus Waldeck-Weiermair Roland Malli Wolfgang F. Graier
author_sort	Benjamin Gottschalk
title	MICU1 controls cristae junction and spatially anchors mitochondrial Ca2+ uniporter complex
title_short	MICU1 controls cristae junction and spatially anchors mitochondrial Ca2+ uniporter complex
title_full	MICU1 controls cristae junction and spatially anchors mitochondrial Ca2+ uniporter complex
title_fullStr	MICU1 controls cristae junction and spatially anchors mitochondrial Ca2+ uniporter complex
title_full_unstemmed	MICU1 controls cristae junction and spatially anchors mitochondrial Ca2+ uniporter complex
title_sort	micu1 controls cristae junction and spatially anchors mitochondrial ca2+ uniporter complex
publisher	Nature Portfolio
publishDate	2019
url	https://doaj.org/article/6ac9bbcf957c4a56ad8f56403898e532
work_keys_str_mv	AT benjamingottschalk micu1controlscristaejunctionandspatiallyanchorsmitochondrialca2uniportercomplex AT christianeklec micu1controlscristaejunctionandspatiallyanchorsmitochondrialca2uniportercomplex AT gerdleitinger micu1controlscristaejunctionandspatiallyanchorsmitochondrialca2uniportercomplex AT evabernhart micu1controlscristaejunctionandspatiallyanchorsmitochondrialca2uniportercomplex AT renerost micu1controlscristaejunctionandspatiallyanchorsmitochondrialca2uniportercomplex AT helmutbischof micu1controlscristaejunctionandspatiallyanchorsmitochondrialca2uniportercomplex AT corinatmadreitersokolowski micu1controlscristaejunctionandspatiallyanchorsmitochondrialca2uniportercomplex AT snjezanaradulovic micu1controlscristaejunctionandspatiallyanchorsmitochondrialca2uniportercomplex AT emraheroglu micu1controlscristaejunctionandspatiallyanchorsmitochondrialca2uniportercomplex AT wolfgangsattler micu1controlscristaejunctionandspatiallyanchorsmitochondrialca2uniportercomplex AT markuswaldeckweiermair micu1controlscristaejunctionandspatiallyanchorsmitochondrialca2uniportercomplex AT rolandmalli micu1controlscristaejunctionandspatiallyanchorsmitochondrialca2uniportercomplex AT wolfgangfgraier micu1controlscristaejunctionandspatiallyanchorsmitochondrialca2uniportercomplex
_version_	1718390900007108608

MICU1 controls cristae junction and spatially anchors mitochondrial Ca2+ uniporter complex

Ejemplares similares