Anti-TLR7 Antibody Protects Against Lupus Nephritis in NZBWF1 Mice by Targeting B Cells and Patrolling Monocytes
Systemic lupus erythematosus (SLE) is an autoimmune disease characterized by autoantibody production and multiple organ damage. Toll-like receptor 7 (TLR7), an innate immune RNA sensor expressed in monocytes/macrophages, dendritic cells (DCs), and B cells, promotes disease progression. However, litt...
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Autores principales: | Yusuke Murakami, Ryutaro Fukui, Reika Tanaka, Yuji Motoi, Atsuo Kanno, Ryota Sato, Kiyoshi Yamaguchi, Hirofumi Amano, Yoichi Furukawa, Hitoshi Suzuki, Yusuke Suzuki, Naoto Tamura, Naomi Yamashita, Kensuke Miyake |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
Frontiers Media S.A.
2021
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Materias: | |
Acceso en línea: | https://doaj.org/article/6ad713420c2a44b8aaac85ef2150dffd |
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