Hyperhomocysteinemia exacerbates ischemia-reperfusion injury-induced acute kidney injury by mediating oxidative stress, DNA damage, JNK pathway, and apoptosis

Hyperhomocysteinemia (HHcy) plays an important role in the progression of many kidney diseases; however, the relationship between HHcy and ischemia-reperfusion injury (IRI)-induced acute kidney injury (IRI-induced AKI) is far from clear. In this study, we try to investigate the effect and possible m...

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Autores principales:	Zhang Mei, Yuan Jing, Dong Rong, Da Jingjing, Li Qian, Hu Ying, Yu Fangfang, Ran Yan, Zha Yan, Long Yanjun
Formato:	article
Lenguaje:	EN
Publicado:	De Gruyter 2021
Materias:	hyperhomocysteinemia ischemia-reperfusion injury acute kidney injury oxidative stress jnk signaling pathway Biology (General) QH301-705.5
Acceso en línea:	https://doaj.org/article/6ae749d768554ec793bb7800f7d2fca7
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spelling	oai:doaj.org-article:6ae749d768554ec793bb7800f7d2fca72021-12-05T14:10:41ZHyperhomocysteinemia exacerbates ischemia-reperfusion injury-induced acute kidney injury by mediating oxidative stress, DNA damage, JNK pathway, and apoptosis2391-541210.1515/biol-2021-0054https://doaj.org/article/6ae749d768554ec793bb7800f7d2fca72021-05-01T00:00:00Zhttps://doi.org/10.1515/biol-2021-0054https://doaj.org/toc/2391-5412Hyperhomocysteinemia (HHcy) plays an important role in the progression of many kidney diseases; however, the relationship between HHcy and ischemia-reperfusion injury (IRI)-induced acute kidney injury (IRI-induced AKI) is far from clear. In this study, we try to investigate the effect and possible mechanisms of HHcy on IRI-induced AKI.Zhang MeiYuan JingDong RongDa JingjingLi QianHu YingYu FangfangRan YanZha YanLong YanjunDe Gruyterarticlehyperhomocysteinemiaischemia-reperfusion injuryacute kidney injuryoxidative stressjnk signaling pathwayBiology (General)QH301-705.5ENOpen Life Sciences, Vol 16, Iss 1, Pp 537-543 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	hyperhomocysteinemia ischemia-reperfusion injury acute kidney injury oxidative stress jnk signaling pathway Biology (General) QH301-705.5
spellingShingle	hyperhomocysteinemia ischemia-reperfusion injury acute kidney injury oxidative stress jnk signaling pathway Biology (General) QH301-705.5 Zhang Mei Yuan Jing Dong Rong Da Jingjing Li Qian Hu Ying Yu Fangfang Ran Yan Zha Yan Long Yanjun Hyperhomocysteinemia exacerbates ischemia-reperfusion injury-induced acute kidney injury by mediating oxidative stress, DNA damage, JNK pathway, and apoptosis
description	Hyperhomocysteinemia (HHcy) plays an important role in the progression of many kidney diseases; however, the relationship between HHcy and ischemia-reperfusion injury (IRI)-induced acute kidney injury (IRI-induced AKI) is far from clear. In this study, we try to investigate the effect and possible mechanisms of HHcy on IRI-induced AKI.
format	article
author	Zhang Mei Yuan Jing Dong Rong Da Jingjing Li Qian Hu Ying Yu Fangfang Ran Yan Zha Yan Long Yanjun
author_facet	Zhang Mei Yuan Jing Dong Rong Da Jingjing Li Qian Hu Ying Yu Fangfang Ran Yan Zha Yan Long Yanjun
author_sort	Zhang Mei
title	Hyperhomocysteinemia exacerbates ischemia-reperfusion injury-induced acute kidney injury by mediating oxidative stress, DNA damage, JNK pathway, and apoptosis
title_short	Hyperhomocysteinemia exacerbates ischemia-reperfusion injury-induced acute kidney injury by mediating oxidative stress, DNA damage, JNK pathway, and apoptosis
title_full	Hyperhomocysteinemia exacerbates ischemia-reperfusion injury-induced acute kidney injury by mediating oxidative stress, DNA damage, JNK pathway, and apoptosis
title_fullStr	Hyperhomocysteinemia exacerbates ischemia-reperfusion injury-induced acute kidney injury by mediating oxidative stress, DNA damage, JNK pathway, and apoptosis
title_full_unstemmed	Hyperhomocysteinemia exacerbates ischemia-reperfusion injury-induced acute kidney injury by mediating oxidative stress, DNA damage, JNK pathway, and apoptosis
title_sort	hyperhomocysteinemia exacerbates ischemia-reperfusion injury-induced acute kidney injury by mediating oxidative stress, dna damage, jnk pathway, and apoptosis
publisher	De Gruyter
publishDate	2021
url	https://doaj.org/article/6ae749d768554ec793bb7800f7d2fca7
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Hyperhomocysteinemia exacerbates ischemia-reperfusion injury-induced acute kidney injury by mediating oxidative stress, DNA damage, JNK pathway, and apoptosis

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