The Relationship Between Dry Eye in Adults with Indications for Kidney Transplantation and Influence Factors

Nguyen Le Trung,1,2 Pham Quoc Toan,1,3 Le Viet Thang,1,3 Nguyen Dinh Ngan,1,2 Nguyen Chien Thang,1,2 Nguyen Van Cuong,1,2 Nguyen Van Dam,1,2 Hoang Tuan Anh,1,2 Vo Thi Hang,1,2 Nguyen Kien Trung,4 Do Nhu Binh,1,5 Vu Anh Tuan6 1Vietnam Military Medical University, Hanoi, 12108, Vietnam; 2Vietnam Depar...

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Autores principales: Le Trung N, Quoc Toan P, Thang LV, Ngan ND, Chien Thang N, Van Cuong N, Van Dam N, Tuan Anh H, Thi Hang V, Kien Trung N, Nhu Binh D, Anh Tuan V
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Publicado: Dove Medical Press 2021
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spelling oai:doaj.org-article:6aea3adef48f433c9817965abb70829b2021-12-02T17:26:25ZThe Relationship Between Dry Eye in Adults with Indications for Kidney Transplantation and Influence Factors1177-5483https://doaj.org/article/6aea3adef48f433c9817965abb70829b2021-10-01T00:00:00Zhttps://www.dovepress.com/the-relationship-between-dry-eye-in-adults-with-indications-for-kidney-peer-reviewed-fulltext-article-OPTHhttps://doaj.org/toc/1177-5483Nguyen Le Trung,1,2 Pham Quoc Toan,1,3 Le Viet Thang,1,3 Nguyen Dinh Ngan,1,2 Nguyen Chien Thang,1,2 Nguyen Van Cuong,1,2 Nguyen Van Dam,1,2 Hoang Tuan Anh,1,2 Vo Thi Hang,1,2 Nguyen Kien Trung,4 Do Nhu Binh,1,5 Vu Anh Tuan6 1Vietnam Military Medical University, Hanoi, 12108, Vietnam; 2Vietnam Department of Opthalmology, Military Hospital 103, Hanoi, 12108, Vietnam; 3Vietnam Department of Nephrology, Military Hospital 103, Hanoi, 12108, Vietnam; 4Vietnam National Eye Hospital, Hanoi, 11613, Vietnam; 5Vietnam Department of Infectious Diseases, Military Hospital 103, Hanoi, 12108, Vietnam; 6Vietnam Hanoi Medical University, Hanoi, 11601, VietnamCorrespondence: Vu Anh Tuan Email vuanhtuan64@gmail.comPurpose: Patients with end-stage renal failure are susceptible to dry eye disease. This study explores the relationship between dry eye disease and influence factors.Patients and Methods: The control group consisted of 57 healthy subjects who were kidney donors. They were of the same age and sex as the kidney transplant recipients. The outcome variable was the dry eye condition of the participants. The Schirmer test confirmed dry eye disease, TBUT (breakup time test), and the Eye Surface Disease Index (OSDI) questionnaire, using linear regression to evaluate the association.Results: The total number of subjects was 146 (89 kidney recipients and 57 kidney donors). When univariate analysis found the level of visual acuity, the age group involved was statistically significant, while the other factors were not statistically significant. In multivariable logistic regression analysis, age (odds ratio: 2.8, p< 0.05), smoking history (odd ratio: 0.1, p< 0.05), corneal conjunctival calcification (odd ratio: 0.2, p< 0.05); central corneal thickness (odd ratio: 1.02, p< 0.05) is considered to be an influence factor for disease progression.Conclusion: Age group, smoking history, corneal central thickness, and conjunctival calcification are factors for dry eye disease in patients preparing to receive a kidney. These results reinforce the evidence for multifactorial dry eye disease in patients with renal impairment.Keywords: dry eye, renal failure, renal transplant, Hanoi VietnamLe Trung NQuoc Toan PThang LVNgan NDChien Thang NVan Cuong NVan Dam NTuan Anh HThi Hang VKien Trung NNhu Binh DAnh Tuan VDove Medical Pressarticledry eyerenal failurerenal transplanthanoi vietnamOphthalmologyRE1-994ENClinical Ophthalmology, Vol Volume 15, Pp 4327-4332 (2021)
institution DOAJ
collection DOAJ
language EN
topic dry eye
renal failure
renal transplant
hanoi vietnam
Ophthalmology
RE1-994
spellingShingle dry eye
renal failure
renal transplant
hanoi vietnam
Ophthalmology
RE1-994
Le Trung N
Quoc Toan P
Thang LV
Ngan ND
Chien Thang N
Van Cuong N
Van Dam N
Tuan Anh H
Thi Hang V
Kien Trung N
Nhu Binh D
Anh Tuan V
The Relationship Between Dry Eye in Adults with Indications for Kidney Transplantation and Influence Factors
description Nguyen Le Trung,1,2 Pham Quoc Toan,1,3 Le Viet Thang,1,3 Nguyen Dinh Ngan,1,2 Nguyen Chien Thang,1,2 Nguyen Van Cuong,1,2 Nguyen Van Dam,1,2 Hoang Tuan Anh,1,2 Vo Thi Hang,1,2 Nguyen Kien Trung,4 Do Nhu Binh,1,5 Vu Anh Tuan6 1Vietnam Military Medical University, Hanoi, 12108, Vietnam; 2Vietnam Department of Opthalmology, Military Hospital 103, Hanoi, 12108, Vietnam; 3Vietnam Department of Nephrology, Military Hospital 103, Hanoi, 12108, Vietnam; 4Vietnam National Eye Hospital, Hanoi, 11613, Vietnam; 5Vietnam Department of Infectious Diseases, Military Hospital 103, Hanoi, 12108, Vietnam; 6Vietnam Hanoi Medical University, Hanoi, 11601, VietnamCorrespondence: Vu Anh Tuan Email vuanhtuan64@gmail.comPurpose: Patients with end-stage renal failure are susceptible to dry eye disease. This study explores the relationship between dry eye disease and influence factors.Patients and Methods: The control group consisted of 57 healthy subjects who were kidney donors. They were of the same age and sex as the kidney transplant recipients. The outcome variable was the dry eye condition of the participants. The Schirmer test confirmed dry eye disease, TBUT (breakup time test), and the Eye Surface Disease Index (OSDI) questionnaire, using linear regression to evaluate the association.Results: The total number of subjects was 146 (89 kidney recipients and 57 kidney donors). When univariate analysis found the level of visual acuity, the age group involved was statistically significant, while the other factors were not statistically significant. In multivariable logistic regression analysis, age (odds ratio: 2.8, p< 0.05), smoking history (odd ratio: 0.1, p< 0.05), corneal conjunctival calcification (odd ratio: 0.2, p< 0.05); central corneal thickness (odd ratio: 1.02, p< 0.05) is considered to be an influence factor for disease progression.Conclusion: Age group, smoking history, corneal central thickness, and conjunctival calcification are factors for dry eye disease in patients preparing to receive a kidney. These results reinforce the evidence for multifactorial dry eye disease in patients with renal impairment.Keywords: dry eye, renal failure, renal transplant, Hanoi Vietnam
format article
author Le Trung N
Quoc Toan P
Thang LV
Ngan ND
Chien Thang N
Van Cuong N
Van Dam N
Tuan Anh H
Thi Hang V
Kien Trung N
Nhu Binh D
Anh Tuan V
author_facet Le Trung N
Quoc Toan P
Thang LV
Ngan ND
Chien Thang N
Van Cuong N
Van Dam N
Tuan Anh H
Thi Hang V
Kien Trung N
Nhu Binh D
Anh Tuan V
author_sort Le Trung N
title The Relationship Between Dry Eye in Adults with Indications for Kidney Transplantation and Influence Factors
title_short The Relationship Between Dry Eye in Adults with Indications for Kidney Transplantation and Influence Factors
title_full The Relationship Between Dry Eye in Adults with Indications for Kidney Transplantation and Influence Factors
title_fullStr The Relationship Between Dry Eye in Adults with Indications for Kidney Transplantation and Influence Factors
title_full_unstemmed The Relationship Between Dry Eye in Adults with Indications for Kidney Transplantation and Influence Factors
title_sort relationship between dry eye in adults with indications for kidney transplantation and influence factors
publisher Dove Medical Press
publishDate 2021
url https://doaj.org/article/6aea3adef48f433c9817965abb70829b
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