Genetic Biomarkers in Chronic Myeloid Leukemia: What Have We Learned So Far?
Chronic Myeloid Leukemia (CML) is a rare malignant proliferative disease of the hematopoietic system, whose molecular hallmark is the Philadelphia chromosome (Ph). The Ph chromosome originates an aberrant fusion gene with abnormal kinase activity, leading to the buildup of reactive oxygen species an...
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Autores principales: | Bilal Abdulmawjood, Beatriz Costa, Catarina Roma-Rodrigues, Pedro V. Baptista, Alexandra R. Fernandes |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
MDPI AG
2021
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Acceso en línea: | https://doaj.org/article/6aeb2d806be14f6892b1b842b6752cf0 |
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