Sonic Hedgehog gene delivery to the rodent heart promotes angiogenesis via iNOS/netrin-1/PKC pathway.

Sonic Hedgehog gene delivery to the rodent heart promotes angiogenesis via iNOS/netrin-1/PKC pathway.

<h4>Background</h4>We hypothesized that genetic modification of mesenchymal stem cells (MSCs) with Sonic Hedgehog (Shh) transgene, a morphogen during embryonic development and embryonic and adult stem cell growth, improved their survival and angiogenic potential in the ischemic heart via...

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Autores principales: Rafeeq P H Ahmed, Khawaja Husnain Haider, Jiang Shujia, Muhammad Rizwan Afzal, Muhammad Ashraf
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2010
Materias:
Medicine
R
Science
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Acceso en línea:https://doaj.org/article/6af82eafb0034545b626eac4506d5b87
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