Discrete regulatory modules instruct hematopoietic lineage commitment and differentiation

Lineage differentiation and commitment is driven by transcription regulators and chromatin changes. Here the authors report daily profiling of chromatin accessibility and transcriptome changes during human erythropoiesis, relating these changes to lineage potential between erythropoiesis and megakar...

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Autores principales: Grigorios Georgolopoulos, Nikoletta Psatha, Mineo Iwata, Andrew Nishida, Tannishtha Som, Minas Yiangou, John A. Stamatoyannopoulos, Jeff Vierstra
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/6afaac0110ec4c4498a1abfc81a3695b
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