Cell-type-specific genomics reveals histone modification dynamics in mammalian meiosis

Meiotic DSB formation, repair and recombination occur in a continuum of substages termed leptonema, zygonema, pachynema, and diplonema. Here, authors develop a method for isolating pure sub-populations of nuclei that allows for detailed study of meiotic substages.

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Autores principales:	Kwan-Wood Gabriel Lam, Kevin Brick, Gang Cheng, Florencia Pratto, R. Daniel Camerini-Otero
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2019
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/6afc876ac96e49b1b6bf20bf27c669f0
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id	oai:doaj.org-article:6afc876ac96e49b1b6bf20bf27c669f0
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spelling	oai:doaj.org-article:6afc876ac96e49b1b6bf20bf27c669f02021-12-02T17:32:40ZCell-type-specific genomics reveals histone modification dynamics in mammalian meiosis10.1038/s41467-019-11820-72041-1723https://doaj.org/article/6afc876ac96e49b1b6bf20bf27c669f02019-08-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-11820-7https://doaj.org/toc/2041-1723Meiotic DSB formation, repair and recombination occur in a continuum of substages termed leptonema, zygonema, pachynema, and diplonema. Here, authors develop a method for isolating pure sub-populations of nuclei that allows for detailed study of meiotic substages.Kwan-Wood Gabriel LamKevin BrickGang ChengFlorencia PrattoR. Daniel Camerini-OteroNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-11 (2019)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Kwan-Wood Gabriel Lam Kevin Brick Gang Cheng Florencia Pratto R. Daniel Camerini-Otero Cell-type-specific genomics reveals histone modification dynamics in mammalian meiosis
description	Meiotic DSB formation, repair and recombination occur in a continuum of substages termed leptonema, zygonema, pachynema, and diplonema. Here, authors develop a method for isolating pure sub-populations of nuclei that allows for detailed study of meiotic substages.
format	article
author	Kwan-Wood Gabriel Lam Kevin Brick Gang Cheng Florencia Pratto R. Daniel Camerini-Otero
author_facet	Kwan-Wood Gabriel Lam Kevin Brick Gang Cheng Florencia Pratto R. Daniel Camerini-Otero
author_sort	Kwan-Wood Gabriel Lam
title	Cell-type-specific genomics reveals histone modification dynamics in mammalian meiosis
title_short	Cell-type-specific genomics reveals histone modification dynamics in mammalian meiosis
title_full	Cell-type-specific genomics reveals histone modification dynamics in mammalian meiosis
title_fullStr	Cell-type-specific genomics reveals histone modification dynamics in mammalian meiosis
title_full_unstemmed	Cell-type-specific genomics reveals histone modification dynamics in mammalian meiosis
title_sort	cell-type-specific genomics reveals histone modification dynamics in mammalian meiosis
publisher	Nature Portfolio
publishDate	2019
url	https://doaj.org/article/6afc876ac96e49b1b6bf20bf27c669f0
work_keys_str_mv	AT kwanwoodgabriellam celltypespecificgenomicsrevealshistonemodificationdynamicsinmammalianmeiosis AT kevinbrick celltypespecificgenomicsrevealshistonemodificationdynamicsinmammalianmeiosis AT gangcheng celltypespecificgenomicsrevealshistonemodificationdynamicsinmammalianmeiosis AT florenciapratto celltypespecificgenomicsrevealshistonemodificationdynamicsinmammalianmeiosis AT rdanielcameriniotero celltypespecificgenomicsrevealshistonemodificationdynamicsinmammalianmeiosis
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Cell-type-specific genomics reveals histone modification dynamics in mammalian meiosis

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