The Use of Probiotics to Enhance Immunity of Broiler Chicken Against Some Intestinal Infection Pathogens

This study was conducted on120 one day old broiler chicks which were divided into six groups, 20 birds each. Group 1 (control), group 2 (supplemented with probiotic), group 3 (challenged with Salmonella and receive no probiotic), group 4 (challenged with E coli and receive no probiotic), group 5 (ch...

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Autores principales:	Fatma M. Mohamed, Manal H. Thabet, Marwa F. Ali
Formato:	article
Lenguaje:	EN
Publicado:	South Valley University 2019
Materias:	Probiotics Chicken Immunity Pathology Agriculture S Veterinary medicine SF600-1100
Acceso en línea:	https://doaj.org/article/6b008ca3c7ab48c8bc4cd54be208d247
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spelling	oai:doaj.org-article:6b008ca3c7ab48c8bc4cd54be208d2472021-12-02T04:27:17ZThe Use of Probiotics to Enhance Immunity of Broiler Chicken Against Some Intestinal Infection Pathogens10.21608/svu.2019.231412535-18262535-1877https://doaj.org/article/6b008ca3c7ab48c8bc4cd54be208d2472019-03-01T00:00:00Zhttps://svu.journals.ekb.eg/article_23141.htmlhttps://doaj.org/toc/2535-1826https://doaj.org/toc/2535-1877This study was conducted on120 one day old broiler chicks which were divided into six groups, 20 birds each. Group 1 (control), group 2 (supplemented with probiotic), group 3 (challenged with Salmonella and receive no probiotic), group 4 (challenged with E coli and receive no probiotic), group 5 (challenged with Salmonella and supplemented with probiotic), group 6 (challenged with E coli and supplemented with probiotic). The experiment extended for 30 days starting from one-day-old chicks. Body weights, clinical symptoms, haematological analysis and postmortem lesions were demonstrated on 8th, 15th and 30th day of the experiment. Also, histopathological studies of the intestinal mucosa, liver, spleen, thymus and bursa of Fabricius, as well as immunostaining of surface antigens (CD3A in the thymus and CD79A in the spleen and bursae of Fabricius), were also investigated. The current study revealed that supplementation of probiotic alone obviously improved weight gains as compared to the control group. Furthermore, probiotic supplementation decreased the colony forming a unit (CFU) of Salmonella enteritidis and E. coli (strain O2: H45) in the intestinal mucosa. Histopathologically, the intestinal mucosa showed an improvement which indicated by hyperplasia of the lining epithelium and abundance of goblet cells, but this local effect did not extend to other organs in the body that demonstrated mild to severe histopathological changes in challenged groups. The haematological analysis also verified that treatment with probiotics had no significant effect on most blood values (RBCs, WBCs and Hb). However, the differential leucocytic counts were significantly influenced by dietary treatment with probiotics which caused a highly significant decrease in lymphocyte percentage. In conclusion, probiotics obviously improved the growth performance and local immune response in the intestine, however no clear evidence of improvement of the general immune status of the experimental birds.Fatma M. Mohamed Manal H. ThabetMarwa F. AliSouth Valley UniversityarticleProbioticsChickenImmunityPathologyAgricultureSVeterinary medicineSF600-1100ENSVU-International Journal of Veterinary Sciences, Vol 2, Iss 1, Pp 1-19 (2019)
institution	DOAJ
collection	DOAJ
language	EN
topic	Probiotics Chicken Immunity Pathology Agriculture S Veterinary medicine SF600-1100
spellingShingle	Probiotics Chicken Immunity Pathology Agriculture S Veterinary medicine SF600-1100 Fatma M. Mohamed Manal H. Thabet Marwa F. Ali The Use of Probiotics to Enhance Immunity of Broiler Chicken Against Some Intestinal Infection Pathogens
description	This study was conducted on120 one day old broiler chicks which were divided into six groups, 20 birds each. Group 1 (control), group 2 (supplemented with probiotic), group 3 (challenged with Salmonella and receive no probiotic), group 4 (challenged with E coli and receive no probiotic), group 5 (challenged with Salmonella and supplemented with probiotic), group 6 (challenged with E coli and supplemented with probiotic). The experiment extended for 30 days starting from one-day-old chicks. Body weights, clinical symptoms, haematological analysis and postmortem lesions were demonstrated on 8th, 15th and 30th day of the experiment. Also, histopathological studies of the intestinal mucosa, liver, spleen, thymus and bursa of Fabricius, as well as immunostaining of surface antigens (CD3A in the thymus and CD79A in the spleen and bursae of Fabricius), were also investigated. The current study revealed that supplementation of probiotic alone obviously improved weight gains as compared to the control group. Furthermore, probiotic supplementation decreased the colony forming a unit (CFU) of Salmonella enteritidis and E. coli (strain O2: H45) in the intestinal mucosa. Histopathologically, the intestinal mucosa showed an improvement which indicated by hyperplasia of the lining epithelium and abundance of goblet cells, but this local effect did not extend to other organs in the body that demonstrated mild to severe histopathological changes in challenged groups. The haematological analysis also verified that treatment with probiotics had no significant effect on most blood values (RBCs, WBCs and Hb). However, the differential leucocytic counts were significantly influenced by dietary treatment with probiotics which caused a highly significant decrease in lymphocyte percentage. In conclusion, probiotics obviously improved the growth performance and local immune response in the intestine, however no clear evidence of improvement of the general immune status of the experimental birds.
format	article
author	Fatma M. Mohamed Manal H. Thabet Marwa F. Ali
author_facet	Fatma M. Mohamed Manal H. Thabet Marwa F. Ali
author_sort	Fatma M. Mohamed
title	The Use of Probiotics to Enhance Immunity of Broiler Chicken Against Some Intestinal Infection Pathogens
title_short	The Use of Probiotics to Enhance Immunity of Broiler Chicken Against Some Intestinal Infection Pathogens
title_full	The Use of Probiotics to Enhance Immunity of Broiler Chicken Against Some Intestinal Infection Pathogens
title_fullStr	The Use of Probiotics to Enhance Immunity of Broiler Chicken Against Some Intestinal Infection Pathogens
title_full_unstemmed	The Use of Probiotics to Enhance Immunity of Broiler Chicken Against Some Intestinal Infection Pathogens
title_sort	use of probiotics to enhance immunity of broiler chicken against some intestinal infection pathogens
publisher	South Valley University
publishDate	2019
url	https://doaj.org/article/6b008ca3c7ab48c8bc4cd54be208d247
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The Use of Probiotics to Enhance Immunity of Broiler Chicken Against Some Intestinal Infection Pathogens

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