Reversal of olanzapine-induced weight gain in a patient with schizophrenia by switching to asenapine: a case report

Kosuke Okazaki, Kazuhiko Yamamuro, Toshifumi Kishimoto Department of Psychiatry, Nara Medical University School of Medicine, Kashihara, Japan Aims: Antipsychotics are effective for treating schizophrenia, but atypical antipsychotics can cause several adverse side effects including weight gain, hyp...

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Autores principales:	Okazaki K, Yamamuro K, Kishimoto T
Formato:	article
Lenguaje:	EN
Publicado:	Dove Medical Press 2017
Materias:	Olanzapine Weight gain Schizophrenia Asenapine Neurosciences. Biological psychiatry. Neuropsychiatry RC321-571 Neurology. Diseases of the nervous system RC346-429
Acceso en línea:	https://doaj.org/article/6b0321ee91ec4fd5b2075b9eab97a851
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spelling	oai:doaj.org-article:6b0321ee91ec4fd5b2075b9eab97a8512021-12-02T00:30:30ZReversal of olanzapine-induced weight gain in a patient with schizophrenia by switching to asenapine: a case report1178-2021https://doaj.org/article/6b0321ee91ec4fd5b2075b9eab97a8512017-11-01T00:00:00Zhttps://www.dovepress.com/reversal-of-olanzapine-induced-weight-gain-in-a-patient-with-schizophr-peer-reviewed-article-NDThttps://doaj.org/toc/1178-2021Kosuke Okazaki, Kazuhiko Yamamuro, Toshifumi Kishimoto Department of Psychiatry, Nara Medical University School of Medicine, Kashihara, Japan Aims: Antipsychotics are effective for treating schizophrenia, but atypical antipsychotics can cause several adverse side effects including weight gain, hyperprolactinemia, and extrapyramidal symptoms. Moreover, weight gain increases the risk of metabolic diseases.Methods: We treated a case of olanzapine-induced weight gain in a 41-year-old man with schizophrenia by switching his medication from olanzapine to asenapine.Results: The weight gain improved after switching the medication, from 80.3 to 75.0 kg, a weight loss of 6.6%, and there was no significant worsening of psychological symptoms or other adverse effects.Conclusions: Asenapine might be effective for treating patients with schizophrenia who experience olanzapine-induced weight gain. Keywords: olanzapine, weight gain, schizophrenia, asenapineOkazaki KYamamuro KKishimoto TDove Medical PressarticleOlanzapineWeight gainSchizophreniaAsenapineNeurosciences. Biological psychiatry. NeuropsychiatryRC321-571Neurology. Diseases of the nervous systemRC346-429ENNeuropsychiatric Disease and Treatment, Vol Volume 13, Pp 2837-2840 (2017)
institution	DOAJ
collection	DOAJ
language	EN
topic	Olanzapine Weight gain Schizophrenia Asenapine Neurosciences. Biological psychiatry. Neuropsychiatry RC321-571 Neurology. Diseases of the nervous system RC346-429
spellingShingle	Olanzapine Weight gain Schizophrenia Asenapine Neurosciences. Biological psychiatry. Neuropsychiatry RC321-571 Neurology. Diseases of the nervous system RC346-429 Okazaki K Yamamuro K Kishimoto T Reversal of olanzapine-induced weight gain in a patient with schizophrenia by switching to asenapine: a case report
description	Kosuke Okazaki, Kazuhiko Yamamuro, Toshifumi Kishimoto Department of Psychiatry, Nara Medical University School of Medicine, Kashihara, Japan Aims: Antipsychotics are effective for treating schizophrenia, but atypical antipsychotics can cause several adverse side effects including weight gain, hyperprolactinemia, and extrapyramidal symptoms. Moreover, weight gain increases the risk of metabolic diseases.Methods: We treated a case of olanzapine-induced weight gain in a 41-year-old man with schizophrenia by switching his medication from olanzapine to asenapine.Results: The weight gain improved after switching the medication, from 80.3 to 75.0 kg, a weight loss of 6.6%, and there was no significant worsening of psychological symptoms or other adverse effects.Conclusions: Asenapine might be effective for treating patients with schizophrenia who experience olanzapine-induced weight gain. Keywords: olanzapine, weight gain, schizophrenia, asenapine
format	article
author	Okazaki K Yamamuro K Kishimoto T
author_facet	Okazaki K Yamamuro K Kishimoto T
author_sort	Okazaki K
title	Reversal of olanzapine-induced weight gain in a patient with schizophrenia by switching to asenapine: a case report
title_short	Reversal of olanzapine-induced weight gain in a patient with schizophrenia by switching to asenapine: a case report
title_full	Reversal of olanzapine-induced weight gain in a patient with schizophrenia by switching to asenapine: a case report
title_fullStr	Reversal of olanzapine-induced weight gain in a patient with schizophrenia by switching to asenapine: a case report
title_full_unstemmed	Reversal of olanzapine-induced weight gain in a patient with schizophrenia by switching to asenapine: a case report
title_sort	reversal of olanzapine-induced weight gain in a patient with schizophrenia by switching to asenapine: a case report
publisher	Dove Medical Press
publishDate	2017
url	https://doaj.org/article/6b0321ee91ec4fd5b2075b9eab97a851
work_keys_str_mv	AT okazakik reversalofolanzapineinducedweightgaininapatientwithschizophreniabyswitchingtoasenapineacasereport AT yamamurok reversalofolanzapineinducedweightgaininapatientwithschizophreniabyswitchingtoasenapineacasereport AT kishimotot reversalofolanzapineinducedweightgaininapatientwithschizophreniabyswitchingtoasenapineacasereport
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Reversal of olanzapine-induced weight gain in a patient with schizophrenia by switching to asenapine: a case report

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