Validation and cross-cultural adaptation of the depression Patient’s Health Questionnaire – 9 in the Romanian population of patients with Type 2 Diabetes Mellitus

Nicoleta Lupascu,1 Bogdan Timar,2,3 Alin Albai,1,3 Deiana Roman,1 Ovidiu Potre,4,5 Romulus Timar1,31Second Department of Internal Medicine, “Victor Babes” University of Medicine and Pharmacy, Timisoara, Romania; 2Department of Functional Sciences, “Victor Babes&rdqu...

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Autores principales: Lupascu N, Timar B, Albai A, Roman D, Potre O, Timar R
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Publicado: Dove Medical Press 2019
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spelling oai:doaj.org-article:6b080d866acf4312a123fc0846e90f9f2021-12-02T06:51:53ZValidation and cross-cultural adaptation of the depression Patient’s Health Questionnaire – 9 in the Romanian population of patients with Type 2 Diabetes Mellitus1178-7007https://doaj.org/article/6b080d866acf4312a123fc0846e90f9f2019-05-01T00:00:00Zhttps://www.dovepress.com/validation-and-cross-cultural-adaptation-of-the-depression-patients-he-peer-reviewed-article-DMSOhttps://doaj.org/toc/1178-7007Nicoleta Lupascu,1 Bogdan Timar,2,3 Alin Albai,1,3 Deiana Roman,1 Ovidiu Potre,4,5 Romulus Timar1,31Second Department of Internal Medicine, “Victor Babes” University of Medicine and Pharmacy, Timisoara, Romania; 2Department of Functional Sciences, “Victor Babes” University of Medicine and Pharmacy, Timisoara, Romania; 3Department of Diabetes and Metabolic Diseases, “Pius Brinzeu” Emergency Hospital, Timisoara, Romania; 4First Department of Internal Medicine, “Victor Babes” University of Medicine and Pharmacy, Timisoara, Romania; 5Department of Hematology, Municipal Emergency Hospital, Timisoara, RomaniaPurpose: To validate and to evaluate the performance in depression screening of the Patient’s Health Questionnaire – 9 (PHQ-9) for Romanian patients with Type 2 Diabetes Mellitus (T2DM).Patients and methods: In a consecutive-case, population-based, non-interventional study design 107 hospitalized patients with T2DM were enrolled. The PHQ-9 was evaluated in regard to its acceptability, ceiling and floor effect, reproducibility, and test–retest performance. Its validity was tested by comparing it to the Beck depression scale, which is a validated tool for this patient population.Results: The PHQ-9 questionnaire had an excellent acceptability, having no non-responders for any of its questions and a median completion time of 3 mins and 12 s, a good reliability with a Cronbach’s α=0.897 [0.865–0.924] 95%CI, a good test–retest performance (Spearman’s rho =0.972; p<0.001 between two administrations of the test) without any ceiling or floor effect observed for the total score. At the same time, the score demonstrated a good validity when compared to a more complex and previously validated instrument like the Beck depression scale (Spearman’s rho =0.777; p<0.001). The limits of agreement (Bland-Altmann analysis) between the two measurements are 2.6 to −2.5 points.Conclusion: The PHQ-9 is a valid, useful instrument for depression screening in Romanian patients with T2DM.Keywords: questionnaire validation, depression screening, chronic diseases, screening instrument, depression in diabetesLupascu NTimar BAlbai ARoman DPotre OTimar RDove Medical Pressarticlequestionnaire validationdepression screeningchronic diseasesscreening instrumentdepression in diabetesSpecialties of internal medicineRC581-951ENDiabetes, Metabolic Syndrome and Obesity: Targets and Therapy, Vol Volume 12, Pp 841-849 (2019)
institution DOAJ
collection DOAJ
language EN
topic questionnaire validation
depression screening
chronic diseases
screening instrument
depression in diabetes
Specialties of internal medicine
RC581-951
spellingShingle questionnaire validation
depression screening
chronic diseases
screening instrument
depression in diabetes
Specialties of internal medicine
RC581-951
Lupascu N
Timar B
Albai A
Roman D
Potre O
Timar R
Validation and cross-cultural adaptation of the depression Patient’s Health Questionnaire – 9 in the Romanian population of patients with Type 2 Diabetes Mellitus
description Nicoleta Lupascu,1 Bogdan Timar,2,3 Alin Albai,1,3 Deiana Roman,1 Ovidiu Potre,4,5 Romulus Timar1,31Second Department of Internal Medicine, “Victor Babes” University of Medicine and Pharmacy, Timisoara, Romania; 2Department of Functional Sciences, “Victor Babes” University of Medicine and Pharmacy, Timisoara, Romania; 3Department of Diabetes and Metabolic Diseases, “Pius Brinzeu” Emergency Hospital, Timisoara, Romania; 4First Department of Internal Medicine, “Victor Babes” University of Medicine and Pharmacy, Timisoara, Romania; 5Department of Hematology, Municipal Emergency Hospital, Timisoara, RomaniaPurpose: To validate and to evaluate the performance in depression screening of the Patient’s Health Questionnaire – 9 (PHQ-9) for Romanian patients with Type 2 Diabetes Mellitus (T2DM).Patients and methods: In a consecutive-case, population-based, non-interventional study design 107 hospitalized patients with T2DM were enrolled. The PHQ-9 was evaluated in regard to its acceptability, ceiling and floor effect, reproducibility, and test–retest performance. Its validity was tested by comparing it to the Beck depression scale, which is a validated tool for this patient population.Results: The PHQ-9 questionnaire had an excellent acceptability, having no non-responders for any of its questions and a median completion time of 3 mins and 12 s, a good reliability with a Cronbach’s α=0.897 [0.865–0.924] 95%CI, a good test–retest performance (Spearman’s rho =0.972; p<0.001 between two administrations of the test) without any ceiling or floor effect observed for the total score. At the same time, the score demonstrated a good validity when compared to a more complex and previously validated instrument like the Beck depression scale (Spearman’s rho =0.777; p<0.001). The limits of agreement (Bland-Altmann analysis) between the two measurements are 2.6 to −2.5 points.Conclusion: The PHQ-9 is a valid, useful instrument for depression screening in Romanian patients with T2DM.Keywords: questionnaire validation, depression screening, chronic diseases, screening instrument, depression in diabetes
format article
author Lupascu N
Timar B
Albai A
Roman D
Potre O
Timar R
author_facet Lupascu N
Timar B
Albai A
Roman D
Potre O
Timar R
author_sort Lupascu N
title Validation and cross-cultural adaptation of the depression Patient’s Health Questionnaire – 9 in the Romanian population of patients with Type 2 Diabetes Mellitus
title_short Validation and cross-cultural adaptation of the depression Patient’s Health Questionnaire – 9 in the Romanian population of patients with Type 2 Diabetes Mellitus
title_full Validation and cross-cultural adaptation of the depression Patient’s Health Questionnaire – 9 in the Romanian population of patients with Type 2 Diabetes Mellitus
title_fullStr Validation and cross-cultural adaptation of the depression Patient’s Health Questionnaire – 9 in the Romanian population of patients with Type 2 Diabetes Mellitus
title_full_unstemmed Validation and cross-cultural adaptation of the depression Patient’s Health Questionnaire – 9 in the Romanian population of patients with Type 2 Diabetes Mellitus
title_sort validation and cross-cultural adaptation of the depression patient’s health questionnaire – 9 in the romanian population of patients with type 2 diabetes mellitus
publisher Dove Medical Press
publishDate 2019
url https://doaj.org/article/6b080d866acf4312a123fc0846e90f9f
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