Aptamer-Conjugated Quantum Dot Optical Biosensors: Strategies and Applications
Quantum dots (QDs) represent the promising new generation of luminophores owing to their size-, composition-, and surface-dependent tunable photoluminescence (PL) and photochemical stability. The development of various QD composites with high PL and good biocompatibility has facilitated the use of a...
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MDPI AG
2021
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oai:doaj.org-article:6b0c7a14e00b4880ba3fc611d0772bd32021-11-25T17:13:39ZAptamer-Conjugated Quantum Dot Optical Biosensors: Strategies and Applications10.3390/chemosensors91103182227-9040https://doaj.org/article/6b0c7a14e00b4880ba3fc611d0772bd32021-11-01T00:00:00Zhttps://www.mdpi.com/2227-9040/9/11/318https://doaj.org/toc/2227-9040Quantum dots (QDs) represent the promising new generation of luminophores owing to their size-, composition-, and surface-dependent tunable photoluminescence (PL) and photochemical stability. The development of various QD composites with high PL and good biocompatibility has facilitated the use of aptamer-functionalized QD biosensors for highly sensitive and specific detection of molecules in clinical and environmental settings. In addition to describing the recent advances in aptamer-based QD biosensor technology for the detection of diverse chemicals and biomolecules, this review provides recent examples of sensing strategies based on optical signal enhancement and quenching of QDs. It also discusses potential strategies for the development of biosensors to widen their practical applications across various scientific and technological fields.Dongmin KimSeungmin YooMDPI AGarticlequantum dotaptamerdetectionbiomoleculephotoluminescencebiosensorBiochemistryQD415-436ENChemosensors, Vol 9, Iss 318, p 318 (2021) |
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quantum dot aptamer detection biomolecule photoluminescence biosensor Biochemistry QD415-436 |
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quantum dot aptamer detection biomolecule photoluminescence biosensor Biochemistry QD415-436 Dongmin Kim Seungmin Yoo Aptamer-Conjugated Quantum Dot Optical Biosensors: Strategies and Applications |
description |
Quantum dots (QDs) represent the promising new generation of luminophores owing to their size-, composition-, and surface-dependent tunable photoluminescence (PL) and photochemical stability. The development of various QD composites with high PL and good biocompatibility has facilitated the use of aptamer-functionalized QD biosensors for highly sensitive and specific detection of molecules in clinical and environmental settings. In addition to describing the recent advances in aptamer-based QD biosensor technology for the detection of diverse chemicals and biomolecules, this review provides recent examples of sensing strategies based on optical signal enhancement and quenching of QDs. It also discusses potential strategies for the development of biosensors to widen their practical applications across various scientific and technological fields. |
format |
article |
author |
Dongmin Kim Seungmin Yoo |
author_facet |
Dongmin Kim Seungmin Yoo |
author_sort |
Dongmin Kim |
title |
Aptamer-Conjugated Quantum Dot Optical Biosensors: Strategies and Applications |
title_short |
Aptamer-Conjugated Quantum Dot Optical Biosensors: Strategies and Applications |
title_full |
Aptamer-Conjugated Quantum Dot Optical Biosensors: Strategies and Applications |
title_fullStr |
Aptamer-Conjugated Quantum Dot Optical Biosensors: Strategies and Applications |
title_full_unstemmed |
Aptamer-Conjugated Quantum Dot Optical Biosensors: Strategies and Applications |
title_sort |
aptamer-conjugated quantum dot optical biosensors: strategies and applications |
publisher |
MDPI AG |
publishDate |
2021 |
url |
https://doaj.org/article/6b0c7a14e00b4880ba3fc611d0772bd3 |
work_keys_str_mv |
AT dongminkim aptamerconjugatedquantumdotopticalbiosensorsstrategiesandapplications AT seungminyoo aptamerconjugatedquantumdotopticalbiosensorsstrategiesandapplications |
_version_ |
1718412594803376128 |