Aptamer-Conjugated Quantum Dot Optical Biosensors: Strategies and Applications

Quantum dots (QDs) represent the promising new generation of luminophores owing to their size-, composition-, and surface-dependent tunable photoluminescence (PL) and photochemical stability. The development of various QD composites with high PL and good biocompatibility has facilitated the use of a...

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Autores principales: Dongmin Kim, Seungmin Yoo
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Lenguaje:EN
Publicado: MDPI AG 2021
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Acceso en línea:https://doaj.org/article/6b0c7a14e00b4880ba3fc611d0772bd3
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spelling oai:doaj.org-article:6b0c7a14e00b4880ba3fc611d0772bd32021-11-25T17:13:39ZAptamer-Conjugated Quantum Dot Optical Biosensors: Strategies and Applications10.3390/chemosensors91103182227-9040https://doaj.org/article/6b0c7a14e00b4880ba3fc611d0772bd32021-11-01T00:00:00Zhttps://www.mdpi.com/2227-9040/9/11/318https://doaj.org/toc/2227-9040Quantum dots (QDs) represent the promising new generation of luminophores owing to their size-, composition-, and surface-dependent tunable photoluminescence (PL) and photochemical stability. The development of various QD composites with high PL and good biocompatibility has facilitated the use of aptamer-functionalized QD biosensors for highly sensitive and specific detection of molecules in clinical and environmental settings. In addition to describing the recent advances in aptamer-based QD biosensor technology for the detection of diverse chemicals and biomolecules, this review provides recent examples of sensing strategies based on optical signal enhancement and quenching of QDs. It also discusses potential strategies for the development of biosensors to widen their practical applications across various scientific and technological fields.Dongmin KimSeungmin YooMDPI AGarticlequantum dotaptamerdetectionbiomoleculephotoluminescencebiosensorBiochemistryQD415-436ENChemosensors, Vol 9, Iss 318, p 318 (2021)
institution DOAJ
collection DOAJ
language EN
topic quantum dot
aptamer
detection
biomolecule
photoluminescence
biosensor
Biochemistry
QD415-436
spellingShingle quantum dot
aptamer
detection
biomolecule
photoluminescence
biosensor
Biochemistry
QD415-436
Dongmin Kim
Seungmin Yoo
Aptamer-Conjugated Quantum Dot Optical Biosensors: Strategies and Applications
description Quantum dots (QDs) represent the promising new generation of luminophores owing to their size-, composition-, and surface-dependent tunable photoluminescence (PL) and photochemical stability. The development of various QD composites with high PL and good biocompatibility has facilitated the use of aptamer-functionalized QD biosensors for highly sensitive and specific detection of molecules in clinical and environmental settings. In addition to describing the recent advances in aptamer-based QD biosensor technology for the detection of diverse chemicals and biomolecules, this review provides recent examples of sensing strategies based on optical signal enhancement and quenching of QDs. It also discusses potential strategies for the development of biosensors to widen their practical applications across various scientific and technological fields.
format article
author Dongmin Kim
Seungmin Yoo
author_facet Dongmin Kim
Seungmin Yoo
author_sort Dongmin Kim
title Aptamer-Conjugated Quantum Dot Optical Biosensors: Strategies and Applications
title_short Aptamer-Conjugated Quantum Dot Optical Biosensors: Strategies and Applications
title_full Aptamer-Conjugated Quantum Dot Optical Biosensors: Strategies and Applications
title_fullStr Aptamer-Conjugated Quantum Dot Optical Biosensors: Strategies and Applications
title_full_unstemmed Aptamer-Conjugated Quantum Dot Optical Biosensors: Strategies and Applications
title_sort aptamer-conjugated quantum dot optical biosensors: strategies and applications
publisher MDPI AG
publishDate 2021
url https://doaj.org/article/6b0c7a14e00b4880ba3fc611d0772bd3
work_keys_str_mv AT dongminkim aptamerconjugatedquantumdotopticalbiosensorsstrategiesandapplications
AT seungminyoo aptamerconjugatedquantumdotopticalbiosensorsstrategiesandapplications
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