Structural elements of a pH-sensitive inhibitor binding site in NMDA receptors
Context-dependent inhibition of NMDA receptors has important therapeutic implications for treatment of neurological diseases. Here, the authors use structural biology and biophysics to describe the basis for pH-dependent inhibition for a class of allosteric NMDAR inhibitors, called the 93-series.
Saved in:
| Main Authors: | , , , , , , , , |
|---|---|
| Format: | article |
| Language: | EN |
| Published: |
Nature Portfolio
2019
|
| Subjects: | |
| Online Access: | https://doaj.org/article/6b226358d0264cea8bca51d4ed185d0d |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|