Evaluation of a novel, multi-functional inhibitor compound for prevention of biofilm formation on carbon steel in marine environments

Abstract Chemical biocides remain the most effective mitigation strategy against microbiologically influenced corrosion (MIC), one of the costliest and most pervasive forms of corrosion in industry. However, toxicity and environmental concerns associated with these compounds are encouraging the deve...

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Autores principales:	Benjamin Tuck, Elizabeth Watkin, Maria Forsyth, Anthony Somers, Mahdi Ghorbani, Laura L. Machuca
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Medicine R Science Q
Acceso en línea:	https://doaj.org/article/6b25811c51d248d894d01544463ec01a
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spelling	oai:doaj.org-article:6b25811c51d248d894d01544463ec01a2021-12-02T18:49:28ZEvaluation of a novel, multi-functional inhibitor compound for prevention of biofilm formation on carbon steel in marine environments10.1038/s41598-021-94827-92045-2322https://doaj.org/article/6b25811c51d248d894d01544463ec01a2021-08-01T00:00:00Zhttps://doi.org/10.1038/s41598-021-94827-9https://doaj.org/toc/2045-2322Abstract Chemical biocides remain the most effective mitigation strategy against microbiologically influenced corrosion (MIC), one of the costliest and most pervasive forms of corrosion in industry. However, toxicity and environmental concerns associated with these compounds are encouraging the development of more environmentally friendly MIC inhibitors. In this study, we evaluated the antimicrobial effect of a novel, multi-functional organic corrosion inhibitor (OCI) compound, cetrimonium trans-4-hydroxy-cinnamate (CTA-4OHcinn). Attachment of three bacterial strains, Shewanella chilikensis, Pseudomonas balearica and Klebsiella pneumoniae was evaluated on wet-ground (120 grit finish) and pre-oxidised carbon steel surfaces (AISI 1030), in the presence and absence of the new OCI compound. Our study revealed that all strains preferentially attached to pre-oxidised surfaces as indicated by confocal laser scanning microscopy, scanning electron microscopy and standard colony forming unit (CFU) quantification assays. The inhibitor compound at 10 mM demonstrated 100% reduction in S. chilikensis attachment independent of initial surface condition, while the other two strains were reduced by at least 99.7% of the original viable cell number. Our results demonstrate that CTA-4OHcinn is biocidal active and has promise as a multifunctional, environmentally sound MIC inhibitor for industrial applications.Benjamin TuckElizabeth WatkinMaria ForsythAnthony SomersMahdi GhorbaniLaura L. MachucaNature PortfolioarticleMedicineRScienceQENScientific Reports, Vol 11, Iss 1, Pp 1-12 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine R Science Q
spellingShingle	Medicine R Science Q Benjamin Tuck Elizabeth Watkin Maria Forsyth Anthony Somers Mahdi Ghorbani Laura L. Machuca Evaluation of a novel, multi-functional inhibitor compound for prevention of biofilm formation on carbon steel in marine environments
description	Abstract Chemical biocides remain the most effective mitigation strategy against microbiologically influenced corrosion (MIC), one of the costliest and most pervasive forms of corrosion in industry. However, toxicity and environmental concerns associated with these compounds are encouraging the development of more environmentally friendly MIC inhibitors. In this study, we evaluated the antimicrobial effect of a novel, multi-functional organic corrosion inhibitor (OCI) compound, cetrimonium trans-4-hydroxy-cinnamate (CTA-4OHcinn). Attachment of three bacterial strains, Shewanella chilikensis, Pseudomonas balearica and Klebsiella pneumoniae was evaluated on wet-ground (120 grit finish) and pre-oxidised carbon steel surfaces (AISI 1030), in the presence and absence of the new OCI compound. Our study revealed that all strains preferentially attached to pre-oxidised surfaces as indicated by confocal laser scanning microscopy, scanning electron microscopy and standard colony forming unit (CFU) quantification assays. The inhibitor compound at 10 mM demonstrated 100% reduction in S. chilikensis attachment independent of initial surface condition, while the other two strains were reduced by at least 99.7% of the original viable cell number. Our results demonstrate that CTA-4OHcinn is biocidal active and has promise as a multifunctional, environmentally sound MIC inhibitor for industrial applications.
format	article
author	Benjamin Tuck Elizabeth Watkin Maria Forsyth Anthony Somers Mahdi Ghorbani Laura L. Machuca
author_facet	Benjamin Tuck Elizabeth Watkin Maria Forsyth Anthony Somers Mahdi Ghorbani Laura L. Machuca
author_sort	Benjamin Tuck
title	Evaluation of a novel, multi-functional inhibitor compound for prevention of biofilm formation on carbon steel in marine environments
title_short	Evaluation of a novel, multi-functional inhibitor compound for prevention of biofilm formation on carbon steel in marine environments
title_full	Evaluation of a novel, multi-functional inhibitor compound for prevention of biofilm formation on carbon steel in marine environments
title_fullStr	Evaluation of a novel, multi-functional inhibitor compound for prevention of biofilm formation on carbon steel in marine environments
title_full_unstemmed	Evaluation of a novel, multi-functional inhibitor compound for prevention of biofilm formation on carbon steel in marine environments
title_sort	evaluation of a novel, multi-functional inhibitor compound for prevention of biofilm formation on carbon steel in marine environments
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/6b25811c51d248d894d01544463ec01a
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Evaluation of a novel, multi-functional inhibitor compound for prevention of biofilm formation on carbon steel in marine environments

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