miR-128-3p reduced acute lung injury induced by sepsis via targeting PEL12

Acute lung injury (ALI) caused by sepsis is clinically a syndrome, which is featured by damage to the alveolar epithelium and endothelium. In this study, we employed mice models of cecal ligation and puncture (CLP) and primary mice pulmonary microvascular endothelial cells (MPVECs) in vitro to inves...

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Autores principales: Liu Shinan, Gao Shuai, Yang Zhaoyu, Zhang Peng
Formato: article
Lenguaje:EN
Publicado: De Gruyter 2021
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R
Acceso en línea:https://doaj.org/article/6b2a1b45f15444ccaf2732a812ca7048
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Sumario:Acute lung injury (ALI) caused by sepsis is clinically a syndrome, which is featured by damage to the alveolar epithelium and endothelium. In this study, we employed mice models of cecal ligation and puncture (CLP) and primary mice pulmonary microvascular endothelial cells (MPVECs) in vitro to investigate the effect of miR-128-3p in ALI caused by sepsis.