CHIMs are versatile cholesterol analogs mimicking and visualizing cholesterol behavior in lipid bilayers and cells

Matos et al characterise previously developed cholesterol analogues, named CHIMs, which can be fluorescently labelled by click-chemistry. They find that CHIMs segregate similarly to cholesterol in lipid bilayers, allow the visualisation of cholesterol dynamics in cells, and can functionally replace...

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Bibliographic Details
Main Authors: Anna L. L. Matos, Fabian Keller, Tristan Wegner, Carla Elizabeth Cadena del Castillo, David Grill, Sergej Kudruk, Anne Spang, Frank Glorius, Andreas Heuer, Volker Gerke
Format: article
Language:EN
Published: Nature Portfolio 2021
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Online Access:https://doaj.org/article/6b36ae3d947f489d9b59bc1192d85ba4
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