The molecular mechanism of the type IVa pilus motors

Bacterial type IVa pili are protein filaments used for motility and protein secretion. Here the authors present crystal structures of theGeobacter metallireducensPilB ATPase in two nucleotide states, and suggest a clockwise rotation of the central sub-pores of PilB that would support the assembly of...

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Autores principales: Matthew McCallum, Stephanie Tammam, Ahmad Khan, Lori L. Burrows, P. Lynne Howell
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2017
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Acceso en línea:https://doaj.org/article/6b3b5867680949b9922cb7cf172605e1
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Sumario:Bacterial type IVa pili are protein filaments used for motility and protein secretion. Here the authors present crystal structures of theGeobacter metallireducensPilB ATPase in two nucleotide states, and suggest a clockwise rotation of the central sub-pores of PilB that would support the assembly of a right-handed helical pilus.