Enriched conditioning expands the regenerative ability of sensory neurons after spinal cord injury via neuronal intrinsic redox signaling
Pre conditioning injury or environmental enrichment have been shown to promote axon regeneration. Here the authors show that environmental enrichment, combined with preconditioning injury promotes regeneration via a redox signalling dependent mechanism.
Guardado en:
| Autores principales: | , , , , , , , , , , , , , |
|---|---|
| Formato: | article |
| Lenguaje: | EN |
| Publicado: |
Nature Portfolio
2020
|
| Materias: | |
| Acceso en línea: | https://doaj.org/article/6b41fe29aefd4cac8cb9f73f6e8e598a |
| Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|
| id |
oai:doaj.org-article:6b41fe29aefd4cac8cb9f73f6e8e598a |
|---|---|
| record_format |
dspace |
| spelling |
oai:doaj.org-article:6b41fe29aefd4cac8cb9f73f6e8e598a2021-12-02T10:48:00ZEnriched conditioning expands the regenerative ability of sensory neurons after spinal cord injury via neuronal intrinsic redox signaling10.1038/s41467-020-20179-z2041-1723https://doaj.org/article/6b41fe29aefd4cac8cb9f73f6e8e598a2020-12-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-20179-zhttps://doaj.org/toc/2041-1723Pre conditioning injury or environmental enrichment have been shown to promote axon regeneration. Here the authors show that environmental enrichment, combined with preconditioning injury promotes regeneration via a redox signalling dependent mechanism.Francesco De VirgiliisThomas H. HutsonIlaria PalmisanoSarah AmachreeJian MiaoLuming ZhouRositsa TodorovaRichard ThompsonMatt C. DanziVance P. LemmonJohn L. BixbyIlka WittigAjay M. ShahSimone Di GiovanniNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-16 (2020) |
| institution |
DOAJ |
| collection |
DOAJ |
| language |
EN |
| topic |
Science Q |
| spellingShingle |
Science Q Francesco De Virgiliis Thomas H. Hutson Ilaria Palmisano Sarah Amachree Jian Miao Luming Zhou Rositsa Todorova Richard Thompson Matt C. Danzi Vance P. Lemmon John L. Bixby Ilka Wittig Ajay M. Shah Simone Di Giovanni Enriched conditioning expands the regenerative ability of sensory neurons after spinal cord injury via neuronal intrinsic redox signaling |
| description |
Pre conditioning injury or environmental enrichment have been shown to promote axon regeneration. Here the authors show that environmental enrichment, combined with preconditioning injury promotes regeneration via a redox signalling dependent mechanism. |
| format |
article |
| author |
Francesco De Virgiliis Thomas H. Hutson Ilaria Palmisano Sarah Amachree Jian Miao Luming Zhou Rositsa Todorova Richard Thompson Matt C. Danzi Vance P. Lemmon John L. Bixby Ilka Wittig Ajay M. Shah Simone Di Giovanni |
| author_facet |
Francesco De Virgiliis Thomas H. Hutson Ilaria Palmisano Sarah Amachree Jian Miao Luming Zhou Rositsa Todorova Richard Thompson Matt C. Danzi Vance P. Lemmon John L. Bixby Ilka Wittig Ajay M. Shah Simone Di Giovanni |
| author_sort |
Francesco De Virgiliis |
| title |
Enriched conditioning expands the regenerative ability of sensory neurons after spinal cord injury via neuronal intrinsic redox signaling |
| title_short |
Enriched conditioning expands the regenerative ability of sensory neurons after spinal cord injury via neuronal intrinsic redox signaling |
| title_full |
Enriched conditioning expands the regenerative ability of sensory neurons after spinal cord injury via neuronal intrinsic redox signaling |
| title_fullStr |
Enriched conditioning expands the regenerative ability of sensory neurons after spinal cord injury via neuronal intrinsic redox signaling |
| title_full_unstemmed |
Enriched conditioning expands the regenerative ability of sensory neurons after spinal cord injury via neuronal intrinsic redox signaling |
| title_sort |
enriched conditioning expands the regenerative ability of sensory neurons after spinal cord injury via neuronal intrinsic redox signaling |
| publisher |
Nature Portfolio |
| publishDate |
2020 |
| url |
https://doaj.org/article/6b41fe29aefd4cac8cb9f73f6e8e598a |
| work_keys_str_mv |
AT francescodevirgiliis enrichedconditioningexpandstheregenerativeabilityofsensoryneuronsafterspinalcordinjuryvianeuronalintrinsicredoxsignaling AT thomashhutson enrichedconditioningexpandstheregenerativeabilityofsensoryneuronsafterspinalcordinjuryvianeuronalintrinsicredoxsignaling AT ilariapalmisano enrichedconditioningexpandstheregenerativeabilityofsensoryneuronsafterspinalcordinjuryvianeuronalintrinsicredoxsignaling AT sarahamachree enrichedconditioningexpandstheregenerativeabilityofsensoryneuronsafterspinalcordinjuryvianeuronalintrinsicredoxsignaling AT jianmiao enrichedconditioningexpandstheregenerativeabilityofsensoryneuronsafterspinalcordinjuryvianeuronalintrinsicredoxsignaling AT lumingzhou enrichedconditioningexpandstheregenerativeabilityofsensoryneuronsafterspinalcordinjuryvianeuronalintrinsicredoxsignaling AT rositsatodorova enrichedconditioningexpandstheregenerativeabilityofsensoryneuronsafterspinalcordinjuryvianeuronalintrinsicredoxsignaling AT richardthompson enrichedconditioningexpandstheregenerativeabilityofsensoryneuronsafterspinalcordinjuryvianeuronalintrinsicredoxsignaling AT mattcdanzi enrichedconditioningexpandstheregenerativeabilityofsensoryneuronsafterspinalcordinjuryvianeuronalintrinsicredoxsignaling AT vanceplemmon enrichedconditioningexpandstheregenerativeabilityofsensoryneuronsafterspinalcordinjuryvianeuronalintrinsicredoxsignaling AT johnlbixby enrichedconditioningexpandstheregenerativeabilityofsensoryneuronsafterspinalcordinjuryvianeuronalintrinsicredoxsignaling AT ilkawittig enrichedconditioningexpandstheregenerativeabilityofsensoryneuronsafterspinalcordinjuryvianeuronalintrinsicredoxsignaling AT ajaymshah enrichedconditioningexpandstheregenerativeabilityofsensoryneuronsafterspinalcordinjuryvianeuronalintrinsicredoxsignaling AT simonedigiovanni enrichedconditioningexpandstheregenerativeabilityofsensoryneuronsafterspinalcordinjuryvianeuronalintrinsicredoxsignaling |
| _version_ |
1718396715465179136 |