Distinct mutations in importin-β family nucleocytoplasmic transport receptors transportin-SR and importin-13 affect specific cargo binding
Abstract Importin-(Imp)β family nucleocytoplasmic transport receptors (NTRs) are supposed to bind to their cargoes through interaction between a confined interface on an NTR and a nuclear localization or export signal (NLS/NES) on a cargo. Although consensus NLS/NES sequence motifs have been defined...
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Auteurs principaux: | Makoto Kimura, Kenichiro Imai, Yuriko Morinaka, Yoshiko Hosono-Sakuma, Paul Horton, Naoko Imamoto |
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Format: | article |
Langue: | EN |
Publié: |
Nature Portfolio
2021
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Accès en ligne: | https://doaj.org/article/6b43ca5febed4816aa0bd0d30fecb8b4 |
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