Short-Term Efficacy of Autologous Cellular Micrografts in Male and Female Androgenetic Alopecia: A Retrospective Cohort Study

Shadi Zari Department of Dermatology, Faculty of Medicine, University of Jeddah, Jeddah, Saudi ArabiaCorrespondence: Shadi Zari Email shadizarimd@gmail.comPurpose: Autologous cellular micrografts (ACM) is a novel treatment method in hair loss, and few data are available regarding its efficacy. The p...

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Autor principal:	Zari S
Formato:	article
Lenguaje:	EN
Publicado:	Dove Medical Press 2021
Materias:	androgenetic alopecia pattern hair loss autologous cellular micrografts efficacy regrowth Dermatology RL1-803
Acceso en línea:	https://doaj.org/article/6b4402a412494952b8c8e5adb36f873d
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spelling	oai:doaj.org-article:6b4402a412494952b8c8e5adb36f873d2021-11-18T19:40:26ZShort-Term Efficacy of Autologous Cellular Micrografts in Male and Female Androgenetic Alopecia: A Retrospective Cohort Study1178-7015https://doaj.org/article/6b4402a412494952b8c8e5adb36f873d2021-11-01T00:00:00Zhttps://www.dovepress.com/short-term-efficacy-of-autologous-cellular-micrografts-in-male-and-fem-peer-reviewed-fulltext-article-CCIDhttps://doaj.org/toc/1178-7015Shadi Zari Department of Dermatology, Faculty of Medicine, University of Jeddah, Jeddah, Saudi ArabiaCorrespondence: Shadi Zari Email shadizarimd@gmail.comPurpose: Autologous cellular micrografts (ACM) is a novel treatment method in hair loss, and few data are available regarding its efficacy. The present study was carried out to assess the short-term clinical efficacy of a single application of ACM in the treatment of male and female androgenetic alopecia (AGA).Materials and Methods: This was a single-center retrospective study involving 140 consecutive adults with confirmed AGA, who received a single session of ACM (Regenera Activa®). Efficacy was evaluated 1– 6 months after treatment, by analyzing the change of trichometry parameters, which were assessed using TrichoScan digital image analysis.Results: Depending on the scalp region, there was increase in mean hair density by 4.5– 7.12 hair/cm2, average hair thickness by 0.96– 1.88 μm, % thick hair by 1.74– 3.26%, and mean number of follicular units by 1.30– 2.77, resulting in an increase of cumulative hair thickness by 0.48– 0.56 unit. Additionally, the frontal region showed a significant decrease in % thin hair (− 1.81%, p = 0.037) and yellow dots (− 1.93 N/cm2, p = 0.003). A favorable response was observed in 66.4% of the participants in the frontal region. Further, a gender-specific effect of treatment was observed.Conclusion: ACM is a promising treatment in AGA with a short-term favorable response observed in up to approximately two-thirds of patients.Keywords: androgenetic alopecia, pattern hair loss, autologous cellular micrografts, efficacy, regrowthZari SDove Medical Pressarticleandrogenetic alopeciapattern hair lossautologous cellular micrograftsefficacyregrowthDermatologyRL1-803ENClinical, Cosmetic and Investigational Dermatology, Vol Volume 14, Pp 1725-1736 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	androgenetic alopecia pattern hair loss autologous cellular micrografts efficacy regrowth Dermatology RL1-803
spellingShingle	androgenetic alopecia pattern hair loss autologous cellular micrografts efficacy regrowth Dermatology RL1-803 Zari S Short-Term Efficacy of Autologous Cellular Micrografts in Male and Female Androgenetic Alopecia: A Retrospective Cohort Study
description	Shadi Zari Department of Dermatology, Faculty of Medicine, University of Jeddah, Jeddah, Saudi ArabiaCorrespondence: Shadi Zari Email shadizarimd@gmail.comPurpose: Autologous cellular micrografts (ACM) is a novel treatment method in hair loss, and few data are available regarding its efficacy. The present study was carried out to assess the short-term clinical efficacy of a single application of ACM in the treatment of male and female androgenetic alopecia (AGA).Materials and Methods: This was a single-center retrospective study involving 140 consecutive adults with confirmed AGA, who received a single session of ACM (Regenera Activa®). Efficacy was evaluated 1– 6 months after treatment, by analyzing the change of trichometry parameters, which were assessed using TrichoScan digital image analysis.Results: Depending on the scalp region, there was increase in mean hair density by 4.5– 7.12 hair/cm2, average hair thickness by 0.96– 1.88 μm, % thick hair by 1.74– 3.26%, and mean number of follicular units by 1.30– 2.77, resulting in an increase of cumulative hair thickness by 0.48– 0.56 unit. Additionally, the frontal region showed a significant decrease in % thin hair (− 1.81%, p = 0.037) and yellow dots (− 1.93 N/cm2, p = 0.003). A favorable response was observed in 66.4% of the participants in the frontal region. Further, a gender-specific effect of treatment was observed.Conclusion: ACM is a promising treatment in AGA with a short-term favorable response observed in up to approximately two-thirds of patients.Keywords: androgenetic alopecia, pattern hair loss, autologous cellular micrografts, efficacy, regrowth
format	article
author	Zari S
author_facet	Zari S
author_sort	Zari S
title	Short-Term Efficacy of Autologous Cellular Micrografts in Male and Female Androgenetic Alopecia: A Retrospective Cohort Study
title_short	Short-Term Efficacy of Autologous Cellular Micrografts in Male and Female Androgenetic Alopecia: A Retrospective Cohort Study
title_full	Short-Term Efficacy of Autologous Cellular Micrografts in Male and Female Androgenetic Alopecia: A Retrospective Cohort Study
title_fullStr	Short-Term Efficacy of Autologous Cellular Micrografts in Male and Female Androgenetic Alopecia: A Retrospective Cohort Study
title_full_unstemmed	Short-Term Efficacy of Autologous Cellular Micrografts in Male and Female Androgenetic Alopecia: A Retrospective Cohort Study
title_sort	short-term efficacy of autologous cellular micrografts in male and female androgenetic alopecia: a retrospective cohort study
publisher	Dove Medical Press
publishDate	2021
url	https://doaj.org/article/6b4402a412494952b8c8e5adb36f873d
work_keys_str_mv	AT zaris shorttermefficacyofautologouscellularmicrograftsinmaleandfemaleandrogeneticalopeciaaretrospectivecohortstudy
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Short-Term Efficacy of Autologous Cellular Micrografts in Male and Female Androgenetic Alopecia: A Retrospective Cohort Study

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