Single cell transcriptome analysis of developing arcuate nucleus neurons uncovers their key developmental regulators

Despite the crucial physiological processes governed by neurons in the hypothalamic arcuate nucleus (ARC), the developmental pathways and regulators for ARC neurons remain understudied. In this study the authors use single cell RNA-seq analyses of mouse embryonic ARC to identify cell type-specific m...

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Autores principales:	Christian Huisman, Hyeyoung Cho, Olivier Brock, Su Jeong Lim, Sung Min Youn, Younjung Park, Sangsoo Kim, Soo-Kyung Lee, Alessio Delogu, Jae W. Lee
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2019
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/6b4870b6855841d49b00bd6bbb2625ca
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spelling	oai:doaj.org-article:6b4870b6855841d49b00bd6bbb2625ca2021-12-02T15:35:55ZSingle cell transcriptome analysis of developing arcuate nucleus neurons uncovers their key developmental regulators10.1038/s41467-019-11667-y2041-1723https://doaj.org/article/6b4870b6855841d49b00bd6bbb2625ca2019-08-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-11667-yhttps://doaj.org/toc/2041-1723Despite the crucial physiological processes governed by neurons in the hypothalamic arcuate nucleus (ARC), the developmental pathways and regulators for ARC neurons remain understudied. In this study the authors use single cell RNA-seq analyses of mouse embryonic ARC to identify cell type-specific markers for developing ARC neurons and give key insight into the underlying developmental pathways and regulators.Christian HuismanHyeyoung ChoOlivier BrockSu Jeong LimSung Min YounYounjung ParkSangsoo KimSoo-Kyung LeeAlessio DeloguJae W. LeeNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-12 (2019)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Christian Huisman Hyeyoung Cho Olivier Brock Su Jeong Lim Sung Min Youn Younjung Park Sangsoo Kim Soo-Kyung Lee Alessio Delogu Jae W. Lee Single cell transcriptome analysis of developing arcuate nucleus neurons uncovers their key developmental regulators
description	Despite the crucial physiological processes governed by neurons in the hypothalamic arcuate nucleus (ARC), the developmental pathways and regulators for ARC neurons remain understudied. In this study the authors use single cell RNA-seq analyses of mouse embryonic ARC to identify cell type-specific markers for developing ARC neurons and give key insight into the underlying developmental pathways and regulators.
format	article
author	Christian Huisman Hyeyoung Cho Olivier Brock Su Jeong Lim Sung Min Youn Younjung Park Sangsoo Kim Soo-Kyung Lee Alessio Delogu Jae W. Lee
author_facet	Christian Huisman Hyeyoung Cho Olivier Brock Su Jeong Lim Sung Min Youn Younjung Park Sangsoo Kim Soo-Kyung Lee Alessio Delogu Jae W. Lee
author_sort	Christian Huisman
title	Single cell transcriptome analysis of developing arcuate nucleus neurons uncovers their key developmental regulators
title_short	Single cell transcriptome analysis of developing arcuate nucleus neurons uncovers their key developmental regulators
title_full	Single cell transcriptome analysis of developing arcuate nucleus neurons uncovers their key developmental regulators
title_fullStr	Single cell transcriptome analysis of developing arcuate nucleus neurons uncovers their key developmental regulators
title_full_unstemmed	Single cell transcriptome analysis of developing arcuate nucleus neurons uncovers their key developmental regulators
title_sort	single cell transcriptome analysis of developing arcuate nucleus neurons uncovers their key developmental regulators
publisher	Nature Portfolio
publishDate	2019
url	https://doaj.org/article/6b4870b6855841d49b00bd6bbb2625ca
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Single cell transcriptome analysis of developing arcuate nucleus neurons uncovers their key developmental regulators

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