Linking a Gene Cluster to Atranorin, a Major Cortical Substance of Lichens, through Genetic Dereplication and Heterologous Expression

Lichens play significant roles in ecosystem function and comprise about 20% of all known fungi. Polyketide-derived natural products accumulate in the cortical and medullary layers of lichen thalli, some of which play key roles in protection from biotic and abiotic stresses (e.g., herbivore attacks...

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Autores principales: Wonyong Kim, Rundong Liu, Sunmin Woo, Kyo Bin Kang, Hyun Park, Young Hyun Yu, Hyung-Ho Ha, Seung-Yoon Oh, Ji Ho Yang, Hangun Kim, Sung-Hwan Yun, Jae-Seoun Hur
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Publicado: American Society for Microbiology 2021
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Acceso en línea:https://doaj.org/article/6b4ac854e75c4e2c90b6f81d7cd344da
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spelling oai:doaj.org-article:6b4ac854e75c4e2c90b6f81d7cd344da2021-11-03T21:15:04ZLinking a Gene Cluster to Atranorin, a Major Cortical Substance of Lichens, through Genetic Dereplication and Heterologous Expression2150-751110.1128/mBio.01111-21https://doaj.org/article/6b4ac854e75c4e2c90b6f81d7cd344da2021-06-01T00:00:00Zhttps://journals.asm.org/doi/10.1128/mBio.01111-21https://doaj.org/toc/2150-7511 Lichens play significant roles in ecosystem function and comprise about 20% of all known fungi. Polyketide-derived natural products accumulate in the cortical and medullary layers of lichen thalli, some of which play key roles in protection from biotic and abiotic stresses (e.g., herbivore attacks and UV irradiation).Wonyong KimRundong LiuSunmin WooKyo Bin KangHyun ParkYoung Hyun YuHyung-Ho HaSeung-Yoon OhJi Ho YangHangun KimSung-Hwan YunJae-Seoun HurAmerican Society for MicrobiologyarticleMicrobiologyQR1-502ENmBio, Vol 12, Iss 3 (2021)
institution DOAJ
collection DOAJ
language EN
topic Microbiology
QR1-502
spellingShingle Microbiology
QR1-502
Wonyong Kim
Rundong Liu
Sunmin Woo
Kyo Bin Kang
Hyun Park
Young Hyun Yu
Hyung-Ho Ha
Seung-Yoon Oh
Ji Ho Yang
Hangun Kim
Sung-Hwan Yun
Jae-Seoun Hur
Linking a Gene Cluster to Atranorin, a Major Cortical Substance of Lichens, through Genetic Dereplication and Heterologous Expression
description Lichens play significant roles in ecosystem function and comprise about 20% of all known fungi. Polyketide-derived natural products accumulate in the cortical and medullary layers of lichen thalli, some of which play key roles in protection from biotic and abiotic stresses (e.g., herbivore attacks and UV irradiation).
format article
author Wonyong Kim
Rundong Liu
Sunmin Woo
Kyo Bin Kang
Hyun Park
Young Hyun Yu
Hyung-Ho Ha
Seung-Yoon Oh
Ji Ho Yang
Hangun Kim
Sung-Hwan Yun
Jae-Seoun Hur
author_facet Wonyong Kim
Rundong Liu
Sunmin Woo
Kyo Bin Kang
Hyun Park
Young Hyun Yu
Hyung-Ho Ha
Seung-Yoon Oh
Ji Ho Yang
Hangun Kim
Sung-Hwan Yun
Jae-Seoun Hur
author_sort Wonyong Kim
title Linking a Gene Cluster to Atranorin, a Major Cortical Substance of Lichens, through Genetic Dereplication and Heterologous Expression
title_short Linking a Gene Cluster to Atranorin, a Major Cortical Substance of Lichens, through Genetic Dereplication and Heterologous Expression
title_full Linking a Gene Cluster to Atranorin, a Major Cortical Substance of Lichens, through Genetic Dereplication and Heterologous Expression
title_fullStr Linking a Gene Cluster to Atranorin, a Major Cortical Substance of Lichens, through Genetic Dereplication and Heterologous Expression
title_full_unstemmed Linking a Gene Cluster to Atranorin, a Major Cortical Substance of Lichens, through Genetic Dereplication and Heterologous Expression
title_sort linking a gene cluster to atranorin, a major cortical substance of lichens, through genetic dereplication and heterologous expression
publisher American Society for Microbiology
publishDate 2021
url https://doaj.org/article/6b4ac854e75c4e2c90b6f81d7cd344da
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