Restenosis After Tack Implantation is Associated with Less Complex Patterns of Restenosis Compared to Stent Implantation

In-stent restenosis is complex, difficult to treat and has led to a ‘leave less metal behind’ approach to femoropopliteal intervention. Postangioplasty dissection often requires scaffolding to maintain patency. The Tack Endovascular System provides minimal-metal dissection repair that preserves futu...

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Autores principales:	Raghu Kolluri, William A Gray, Ehrin Armstrong, Brian C Fowler
Formato:	article
Lenguaje:	EN
Publicado:	Radcliffe Medical Media 2020
Materias:	Diseases of the circulatory (Cardiovascular) system RC666-701
Acceso en línea:	https://doaj.org/article/6b511b786f6a4cb1be60bacaee62ad58
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spelling	oai:doaj.org-article:6b511b786f6a4cb1be60bacaee62ad582021-12-04T16:01:58ZRestenosis After Tack Implantation is Associated with Less Complex Patterns of Restenosis Compared to Stent Implantation10.15420/ver.2019.03.R12516-33022516-3299https://doaj.org/article/6b511b786f6a4cb1be60bacaee62ad582020-01-01T00:00:00Zhttps://www.verjournal.com/articleindex/ver.2019.03.R1https://doaj.org/toc/2516-3299https://doaj.org/toc/2516-3302In-stent restenosis is complex, difficult to treat and has led to a ‘leave less metal behind’ approach to femoropopliteal intervention. Postangioplasty dissection often requires scaffolding to maintain patency. The Tack Endovascular System provides minimal-metal dissection repair that preserves future treatment options. Tack implants are designed to minimise the inflammation and neointimal hyperplasia that lead to in-stent restenosis. An independent angiographic core laboratory evaluated the restenosis patterns in clinically driven target lesion revascularisation (CD-TLR) during the 12 months following the index procedure in the Tack Optimized Balloon Angioplasty (TOBA) II study and compared these results to those published for nitinol stent implantation. Of the 213 patients in TOBA II, 31 (14.6%) required a CD-TLR. Of these, 28 had angiograms that were evaluated by the core laboratory, and 45.2%, 16.1%, and 29% were graded as Tosaka class I, II and III, respectively. There were no significant differences (p>0.05) in lesion length, degree of calcification or dissection class between the three groups. Tack restenotic lesion classification and analysis show a prevalence of both class I and shorter lesions relative to in-stent restenosis, which may be beneficial to long-term patient outcomes.Raghu KolluriWilliam A GrayEhrin ArmstrongBrian C FowlerRadcliffe Medical MediaarticleDiseases of the circulatory (Cardiovascular) systemRC666-701ENVascular and Endovascular Review , Vol 3, Iss , Pp - (2020)
institution	DOAJ
collection	DOAJ
language	EN
topic	Diseases of the circulatory (Cardiovascular) system RC666-701
spellingShingle	Diseases of the circulatory (Cardiovascular) system RC666-701 Raghu Kolluri William A Gray Ehrin Armstrong Brian C Fowler Restenosis After Tack Implantation is Associated with Less Complex Patterns of Restenosis Compared to Stent Implantation
description	In-stent restenosis is complex, difficult to treat and has led to a ‘leave less metal behind’ approach to femoropopliteal intervention. Postangioplasty dissection often requires scaffolding to maintain patency. The Tack Endovascular System provides minimal-metal dissection repair that preserves future treatment options. Tack implants are designed to minimise the inflammation and neointimal hyperplasia that lead to in-stent restenosis. An independent angiographic core laboratory evaluated the restenosis patterns in clinically driven target lesion revascularisation (CD-TLR) during the 12 months following the index procedure in the Tack Optimized Balloon Angioplasty (TOBA) II study and compared these results to those published for nitinol stent implantation. Of the 213 patients in TOBA II, 31 (14.6%) required a CD-TLR. Of these, 28 had angiograms that were evaluated by the core laboratory, and 45.2%, 16.1%, and 29% were graded as Tosaka class I, II and III, respectively. There were no significant differences (p>0.05) in lesion length, degree of calcification or dissection class between the three groups. Tack restenotic lesion classification and analysis show a prevalence of both class I and shorter lesions relative to in-stent restenosis, which may be beneficial to long-term patient outcomes.
format	article
author	Raghu Kolluri William A Gray Ehrin Armstrong Brian C Fowler
author_facet	Raghu Kolluri William A Gray Ehrin Armstrong Brian C Fowler
author_sort	Raghu Kolluri
title	Restenosis After Tack Implantation is Associated with Less Complex Patterns of Restenosis Compared to Stent Implantation
title_short	Restenosis After Tack Implantation is Associated with Less Complex Patterns of Restenosis Compared to Stent Implantation
title_full	Restenosis After Tack Implantation is Associated with Less Complex Patterns of Restenosis Compared to Stent Implantation
title_fullStr	Restenosis After Tack Implantation is Associated with Less Complex Patterns of Restenosis Compared to Stent Implantation
title_full_unstemmed	Restenosis After Tack Implantation is Associated with Less Complex Patterns of Restenosis Compared to Stent Implantation
title_sort	restenosis after tack implantation is associated with less complex patterns of restenosis compared to stent implantation
publisher	Radcliffe Medical Media
publishDate	2020
url	https://doaj.org/article/6b511b786f6a4cb1be60bacaee62ad58
work_keys_str_mv	AT raghukolluri restenosisaftertackimplantationisassociatedwithlesscomplexpatternsofrestenosiscomparedtostentimplantation AT williamagray restenosisaftertackimplantationisassociatedwithlesscomplexpatternsofrestenosiscomparedtostentimplantation AT ehrinarmstrong restenosisaftertackimplantationisassociatedwithlesscomplexpatternsofrestenosiscomparedtostentimplantation AT briancfowler restenosisaftertackimplantationisassociatedwithlesscomplexpatternsofrestenosiscomparedtostentimplantation
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Restenosis After Tack Implantation is Associated with Less Complex Patterns of Restenosis Compared to Stent Implantation

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