Targeting the latent cytomegalovirus reservoir with an antiviral fusion toxin protein
Reactivation of human cytomegalovirus in immunosuppressed transplant patients can cause severe complications. Here, Krishnaet al. show that a fusion toxin protein that specifically binds the viral surface protein US28 can be used to kill latently infected monocytes and their progenitor cells in vitr...
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Main Authors: | B. A. Krishna, K. Spiess, E. L. Poole, B. Lau, S. Voigt, T. N. Kledal, M. M. Rosenkilde, J. H. Sinclair |
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Format: | article |
Language: | EN |
Published: |
Nature Portfolio
2017
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Online Access: | https://doaj.org/article/6b51dc5db95748729925ab3ac515e35e |
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