Lipid peroxidation activity in women with reproductive disorders and chronic endometritis

The research focuses on peculiarities of lipid peroxidation processes in women with reproductive disorders associated with chronic endometritis. The control group included 50 women of reproductive age with chronic endometritis, whose average age was 29.7 ± 4.7years. The comparison group consisted of...

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Autores principales:	I. N. Danusevich, N. A. Kurashova, Y. G. Nadelyaeva, A. A. Geyn
Formato:	article
Lenguaje:	RU
Publicado:	Scientific Сentre for Family Health and Human Reproduction Problems 2016
Materias:	chronic endometritis lipid peroxidation reproductive disorders immune system Science Q
Acceso en línea:	https://doaj.org/article/6b6491cc03874a50b9329b59e014b6a0
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spelling	oai:doaj.org-article:6b6491cc03874a50b9329b59e014b6a02021-11-23T06:14:34ZLipid peroxidation activity in women with reproductive disorders and chronic endometritis2541-94202587-959610.12737/article_590823a410c5d8.60967625https://doaj.org/article/6b6491cc03874a50b9329b59e014b6a02016-05-01T00:00:00Zhttps://www.actabiomedica.ru/jour/article/view/178https://doaj.org/toc/2541-9420https://doaj.org/toc/2587-9596The research focuses on peculiarities of lipid peroxidation processes in women with reproductive disorders associated with chronic endometritis. The control group included 50 women of reproductive age with chronic endometritis, whose average age was 29.7 ± 4.7years. The comparison group consisted of 50 women of the same age with reproductive disorders without chronic endometritis, who had signed informed consent. We followed ethical principles and requirements of the Declaration of Helsinki of the World Medical Association. Insufficient activity of peroxidation processes which is characterized by a decrease in the concentration of primary ((DC - 1.11 ± 0.05 for the control group and 1.43 ± 0.08 for the comparison (p < 0.05)) peroxidation products, an increase in concentration of intermediate ((KD) - 0.53 ± 0.03 and 0.36 ± 0.03 respectively (r < 0,001)) peroxidation products and increased content of double bond substrates: 1.82 ± 0.07 and 1.11 ± 0.07 respectively (r < 0,001) compared to the patients with reproductive disorders without chronic inflammation of the endometrium which therefore indicates the presence of oxidative stress in women with reproductive disorders and chronic endometritis. The results of discriminant analysis showed that the diene conjugates are the most informative indicators of the lipid peroxidation system, indicating the differences between the group of patients with chronic endometritis and the group of patients without inflammation.I. N. DanusevichN. A. KurashovaY. G. NadelyaevaA. A. GeynScientific Сentre for Family Health and Human Reproduction Problemsarticlechronic endometritislipid peroxidationreproductive disordersimmune systemScienceQRUActa Biomedica Scientifica, Vol 1, Iss 3(2), Pp 16-19 (2016)
institution	DOAJ
collection	DOAJ
language	RU
topic	chronic endometritis lipid peroxidation reproductive disorders immune system Science Q
spellingShingle	chronic endometritis lipid peroxidation reproductive disorders immune system Science Q I. N. Danusevich N. A. Kurashova Y. G. Nadelyaeva A. A. Geyn Lipid peroxidation activity in women with reproductive disorders and chronic endometritis
description	The research focuses on peculiarities of lipid peroxidation processes in women with reproductive disorders associated with chronic endometritis. The control group included 50 women of reproductive age with chronic endometritis, whose average age was 29.7 ± 4.7years. The comparison group consisted of 50 women of the same age with reproductive disorders without chronic endometritis, who had signed informed consent. We followed ethical principles and requirements of the Declaration of Helsinki of the World Medical Association. Insufficient activity of peroxidation processes which is characterized by a decrease in the concentration of primary ((DC - 1.11 ± 0.05 for the control group and 1.43 ± 0.08 for the comparison (p < 0.05)) peroxidation products, an increase in concentration of intermediate ((KD) - 0.53 ± 0.03 and 0.36 ± 0.03 respectively (r < 0,001)) peroxidation products and increased content of double bond substrates: 1.82 ± 0.07 and 1.11 ± 0.07 respectively (r < 0,001) compared to the patients with reproductive disorders without chronic inflammation of the endometrium which therefore indicates the presence of oxidative stress in women with reproductive disorders and chronic endometritis. The results of discriminant analysis showed that the diene conjugates are the most informative indicators of the lipid peroxidation system, indicating the differences between the group of patients with chronic endometritis and the group of patients without inflammation.
format	article
author	I. N. Danusevich N. A. Kurashova Y. G. Nadelyaeva A. A. Geyn
author_facet	I. N. Danusevich N. A. Kurashova Y. G. Nadelyaeva A. A. Geyn
author_sort	I. N. Danusevich
title	Lipid peroxidation activity in women with reproductive disorders and chronic endometritis
title_short	Lipid peroxidation activity in women with reproductive disorders and chronic endometritis
title_full	Lipid peroxidation activity in women with reproductive disorders and chronic endometritis
title_fullStr	Lipid peroxidation activity in women with reproductive disorders and chronic endometritis
title_full_unstemmed	Lipid peroxidation activity in women with reproductive disorders and chronic endometritis
title_sort	lipid peroxidation activity in women with reproductive disorders and chronic endometritis
publisher	Scientific Сentre for Family Health and Human Reproduction Problems
publishDate	2016
url	https://doaj.org/article/6b6491cc03874a50b9329b59e014b6a0
work_keys_str_mv	AT indanusevich lipidperoxidationactivityinwomenwithreproductivedisordersandchronicendometritis AT nakurashova lipidperoxidationactivityinwomenwithreproductivedisordersandchronicendometritis AT ygnadelyaeva lipidperoxidationactivityinwomenwithreproductivedisordersandchronicendometritis AT aageyn lipidperoxidationactivityinwomenwithreproductivedisordersandchronicendometritis
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Lipid peroxidation activity in women with reproductive disorders and chronic endometritis

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