Gene expression in human brain implicates sexually dimorphic pathways in autism spectrum disorders

Autism spectrum disorder is approximately 4.5 times more likely to occur in boys than girls. Here, Werling, Geschwind and Parikshak characterized sexually dimorphic gene expression in the non-diseased, post-mortem, adult and prenatal human brain, and show genes expressed at higher levels in males ar...

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Autores principales:	Donna M. Werling, Neelroop N. Parikshak, Daniel H. Geschwind
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2016
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/6b6727ff2fe1413bb656425f561cb443
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spelling	oai:doaj.org-article:6b6727ff2fe1413bb656425f561cb4432021-12-02T17:32:53ZGene expression in human brain implicates sexually dimorphic pathways in autism spectrum disorders10.1038/ncomms107172041-1723https://doaj.org/article/6b6727ff2fe1413bb656425f561cb4432016-02-01T00:00:00Zhttps://doi.org/10.1038/ncomms10717https://doaj.org/toc/2041-1723Autism spectrum disorder is approximately 4.5 times more likely to occur in boys than girls. Here, Werling, Geschwind and Parikshak characterized sexually dimorphic gene expression in the non-diseased, post-mortem, adult and prenatal human brain, and show genes expressed at higher levels in males are significantly enriched for genes upregulated in autistic brain.Donna M. WerlingNeelroop N. ParikshakDaniel H. GeschwindNature PortfolioarticleScienceQENNature Communications, Vol 7, Iss 1, Pp 1-11 (2016)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Donna M. Werling Neelroop N. Parikshak Daniel H. Geschwind Gene expression in human brain implicates sexually dimorphic pathways in autism spectrum disorders
description	Autism spectrum disorder is approximately 4.5 times more likely to occur in boys than girls. Here, Werling, Geschwind and Parikshak characterized sexually dimorphic gene expression in the non-diseased, post-mortem, adult and prenatal human brain, and show genes expressed at higher levels in males are significantly enriched for genes upregulated in autistic brain.
format	article
author	Donna M. Werling Neelroop N. Parikshak Daniel H. Geschwind
author_facet	Donna M. Werling Neelroop N. Parikshak Daniel H. Geschwind
author_sort	Donna M. Werling
title	Gene expression in human brain implicates sexually dimorphic pathways in autism spectrum disorders
title_short	Gene expression in human brain implicates sexually dimorphic pathways in autism spectrum disorders
title_full	Gene expression in human brain implicates sexually dimorphic pathways in autism spectrum disorders
title_fullStr	Gene expression in human brain implicates sexually dimorphic pathways in autism spectrum disorders
title_full_unstemmed	Gene expression in human brain implicates sexually dimorphic pathways in autism spectrum disorders
title_sort	gene expression in human brain implicates sexually dimorphic pathways in autism spectrum disorders
publisher	Nature Portfolio
publishDate	2016
url	https://doaj.org/article/6b6727ff2fe1413bb656425f561cb443
work_keys_str_mv	AT donnamwerling geneexpressioninhumanbrainimplicatessexuallydimorphicpathwaysinautismspectrumdisorders AT neelroopnparikshak geneexpressioninhumanbrainimplicatessexuallydimorphicpathwaysinautismspectrumdisorders AT danielhgeschwind geneexpressioninhumanbrainimplicatessexuallydimorphicpathwaysinautismspectrumdisorders
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Gene expression in human brain implicates sexually dimorphic pathways in autism spectrum disorders

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