A Novel Selective LSD1/KDM1A Inhibitor Epigenetically Blocks Herpes Simplex Virus Lytic Replication and Reactivation from Latency
ABSTRACT Cellular processes requiring access to the DNA genome are regulated by an overlay of epigenetic modifications, including histone modification and chromatin remodeling. Similar to the cellular host, many nuclear DNA viruses that depend upon the host cell’s transcriptional machinery are also...
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| Main Authors: | , , , , , |
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| Format: | article |
| Language: | EN |
| Published: |
American Society for Microbiology
2013
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| Subjects: | |
| Online Access: | https://doaj.org/article/6b6c8ab959fb42f28121b92a4680f7e4 |
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