Optic neuropathy associated with the use of over-the-counter sexual enhancement supplements

Sapir Z Karli, Sophie D Liao, Andrew R Carey, Byron L Lam, Sara T Wester Bascom Palmer Eye Institute, University of Miami Miller School of Medicine, Miami, FL, USA Abstract: This case report details an association of the use of over-the-counter sexual enhancement supplements with atypica...

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Autores principales:	Karli SZ, Liao SD, Carey AR, Lam BL, Wester ST
Formato:	article
Lenguaje:	EN
Publicado:	Dove Medical Press 2014
Materias:	Ophthalmology RE1-994
Acceso en línea:	https://doaj.org/article/6b970a0e6a2143f9ba9351d6015fc080
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spelling	oai:doaj.org-article:6b970a0e6a2143f9ba9351d6015fc0802021-12-02T03:56:15ZOptic neuropathy associated with the use of over-the-counter sexual enhancement supplements1177-5483https://doaj.org/article/6b970a0e6a2143f9ba9351d6015fc0802014-10-01T00:00:00Zhttp://www.dovepress.com/optic-neuropathy-associated-with-the-use-of-over-the-counter-sexual-en-peer-reviewed-article-OPTHhttps://doaj.org/toc/1177-5483 Sapir Z Karli, Sophie D Liao, Andrew R Carey, Byron L Lam, Sara T Wester Bascom Palmer Eye Institute, University of Miami Miller School of Medicine, Miami, FL, USA Abstract: This case report details an association of the use of over-the-counter sexual enhancement supplements with atypical optic neuropathy. A 42-year-old man presented with right-sided headache and vision loss of the right eye, which deteriorated to a single quadrant of hand motion over 11 days. Serial orbital magnetic resonance imaging scans demonstrated progressive orbital optic nerve enhancement extending into the optic canal despite high-dose steroid treatment. The patient eventually admitted to using several over-the-counter sexual enhancement supplements prior to the onset of symptoms and throughout the course of his steroid treatment, which he subsequently discontinued. His vision improved to 20/200 with an expanded visual field. Anterior ischemic optic neuropathy has been reported in association with phosphodiesterase (PDE)-5 inhibitor use, but visual loss in association with unregulated sexual enhancement supplements has not been studied. While one case cannot establish association, our case is suggestive of potential dangers of over-the-counter sexual enhancement supplements, which may contain PDE-5 inhibitors, “male hormones,” and “substances that enhance blood production.” The case also underscores the importance of obtaining a careful history of supplements in patients with optic neuropathies. Keywords: optic neuropathy, PDE-5 inhibitor, sildenafilKarli SZLiao SDCarey ARLam BLWester STDove Medical PressarticleOphthalmologyRE1-994ENClinical Ophthalmology, Vol 2014, Iss default, Pp 2171-2175 (2014)
institution	DOAJ
collection	DOAJ
language	EN
topic	Ophthalmology RE1-994
spellingShingle	Ophthalmology RE1-994 Karli SZ Liao SD Carey AR Lam BL Wester ST Optic neuropathy associated with the use of over-the-counter sexual enhancement supplements
description	Sapir Z Karli, Sophie D Liao, Andrew R Carey, Byron L Lam, Sara T Wester Bascom Palmer Eye Institute, University of Miami Miller School of Medicine, Miami, FL, USA Abstract: This case report details an association of the use of over-the-counter sexual enhancement supplements with atypical optic neuropathy. A 42-year-old man presented with right-sided headache and vision loss of the right eye, which deteriorated to a single quadrant of hand motion over 11 days. Serial orbital magnetic resonance imaging scans demonstrated progressive orbital optic nerve enhancement extending into the optic canal despite high-dose steroid treatment. The patient eventually admitted to using several over-the-counter sexual enhancement supplements prior to the onset of symptoms and throughout the course of his steroid treatment, which he subsequently discontinued. His vision improved to 20/200 with an expanded visual field. Anterior ischemic optic neuropathy has been reported in association with phosphodiesterase (PDE)-5 inhibitor use, but visual loss in association with unregulated sexual enhancement supplements has not been studied. While one case cannot establish association, our case is suggestive of potential dangers of over-the-counter sexual enhancement supplements, which may contain PDE-5 inhibitors, “male hormones,” and “substances that enhance blood production.” The case also underscores the importance of obtaining a careful history of supplements in patients with optic neuropathies. Keywords: optic neuropathy, PDE-5 inhibitor, sildenafil
format	article
author	Karli SZ Liao SD Carey AR Lam BL Wester ST
author_facet	Karli SZ Liao SD Carey AR Lam BL Wester ST
author_sort	Karli SZ
title	Optic neuropathy associated with the use of over-the-counter sexual enhancement supplements
title_short	Optic neuropathy associated with the use of over-the-counter sexual enhancement supplements
title_full	Optic neuropathy associated with the use of over-the-counter sexual enhancement supplements
title_fullStr	Optic neuropathy associated with the use of over-the-counter sexual enhancement supplements
title_full_unstemmed	Optic neuropathy associated with the use of over-the-counter sexual enhancement supplements
title_sort	optic neuropathy associated with the use of over-the-counter sexual enhancement supplements
publisher	Dove Medical Press
publishDate	2014
url	https://doaj.org/article/6b970a0e6a2143f9ba9351d6015fc080
work_keys_str_mv	AT karlisz opticneuropathyassociatedwiththeuseofoverthecountersexualenhancementsupplements AT liaosd opticneuropathyassociatedwiththeuseofoverthecountersexualenhancementsupplements AT careyar opticneuropathyassociatedwiththeuseofoverthecountersexualenhancementsupplements AT lambl opticneuropathyassociatedwiththeuseofoverthecountersexualenhancementsupplements AT westerst opticneuropathyassociatedwiththeuseofoverthecountersexualenhancementsupplements
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Optic neuropathy associated with the use of over-the-counter sexual enhancement supplements

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