Cis-perturbation of cancer drivers by the HTLV-1/BLV proviruses is an early determinant of leukemogenesis

Human T-cell leukaemia virus type-1 and bovine leukaemia virus infect T and B lymphocytes and lead to aggressive leukaemia. Here, the authors show these proviruses integrate near cancer drivers perturbing transcription termination or antisense RNA-dependent interaction, suggesting post-transcription...

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Autores principales:	Nicolas Rosewick, Keith Durkin, Maria Artesi, Ambroise Marçais, Vincent Hahaut, Philip Griebel, Natasa Arsic, Véronique Avettand-Fenoel, Arsène Burny, Carole Charlier, Olivier Hermine, Michel Georges, Anne Van den Broeke
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2017
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/6b9b52670f1446bd8437852e61cda7af
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spelling	oai:doaj.org-article:6b9b52670f1446bd8437852e61cda7af2021-12-02T14:40:57ZCis-perturbation of cancer drivers by the HTLV-1/BLV proviruses is an early determinant of leukemogenesis10.1038/ncomms152642041-1723https://doaj.org/article/6b9b52670f1446bd8437852e61cda7af2017-05-01T00:00:00Zhttps://doi.org/10.1038/ncomms15264https://doaj.org/toc/2041-1723Human T-cell leukaemia virus type-1 and bovine leukaemia virus infect T and B lymphocytes and lead to aggressive leukaemia. Here, the authors show these proviruses integrate near cancer drivers perturbing transcription termination or antisense RNA-dependent interaction, suggesting post-transcriptional mechanisms in some cases.Nicolas RosewickKeith DurkinMaria ArtesiAmbroise MarçaisVincent HahautPhilip GriebelNatasa ArsicVéronique Avettand-FenoelArsène BurnyCarole CharlierOlivier HermineMichel GeorgesAnne Van den BroekeNature PortfolioarticleScienceQENNature Communications, Vol 8, Iss 1, Pp 1-15 (2017)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Nicolas Rosewick Keith Durkin Maria Artesi Ambroise Marçais Vincent Hahaut Philip Griebel Natasa Arsic Véronique Avettand-Fenoel Arsène Burny Carole Charlier Olivier Hermine Michel Georges Anne Van den Broeke Cis-perturbation of cancer drivers by the HTLV-1/BLV proviruses is an early determinant of leukemogenesis
description	Human T-cell leukaemia virus type-1 and bovine leukaemia virus infect T and B lymphocytes and lead to aggressive leukaemia. Here, the authors show these proviruses integrate near cancer drivers perturbing transcription termination or antisense RNA-dependent interaction, suggesting post-transcriptional mechanisms in some cases.
format	article
author	Nicolas Rosewick Keith Durkin Maria Artesi Ambroise Marçais Vincent Hahaut Philip Griebel Natasa Arsic Véronique Avettand-Fenoel Arsène Burny Carole Charlier Olivier Hermine Michel Georges Anne Van den Broeke
author_facet	Nicolas Rosewick Keith Durkin Maria Artesi Ambroise Marçais Vincent Hahaut Philip Griebel Natasa Arsic Véronique Avettand-Fenoel Arsène Burny Carole Charlier Olivier Hermine Michel Georges Anne Van den Broeke
author_sort	Nicolas Rosewick
title	Cis-perturbation of cancer drivers by the HTLV-1/BLV proviruses is an early determinant of leukemogenesis
title_short	Cis-perturbation of cancer drivers by the HTLV-1/BLV proviruses is an early determinant of leukemogenesis
title_full	Cis-perturbation of cancer drivers by the HTLV-1/BLV proviruses is an early determinant of leukemogenesis
title_fullStr	Cis-perturbation of cancer drivers by the HTLV-1/BLV proviruses is an early determinant of leukemogenesis
title_full_unstemmed	Cis-perturbation of cancer drivers by the HTLV-1/BLV proviruses is an early determinant of leukemogenesis
title_sort	cis-perturbation of cancer drivers by the htlv-1/blv proviruses is an early determinant of leukemogenesis
publisher	Nature Portfolio
publishDate	2017
url	https://doaj.org/article/6b9b52670f1446bd8437852e61cda7af
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Cis-perturbation of cancer drivers by the HTLV-1/BLV proviruses is an early determinant of leukemogenesis

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