Therapeutic Strategies in Managing Acute Paraquat Poisoning: A Review Study

Background: Paraquat is an extremely toxic herbicide that causes such severe adverse effects as acute lung injury, pulmonary fibrosis, metabolic acidosis, cardiogenic shock, acute renal failure, and even death. Regarding the high prevalence and mortality rate without a specific antidote in paraquat...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autor principal:	Mohammad Majidi
Formato:	article
Lenguaje:	EN
Publicado:	Shaheed Beheshti University of Medical Sciences 2021
Materias:	herbicides paraquat poisoning therapeutics Medicine (General) R5-920 Toxicology. Poisons RA1190-1270
Acceso en línea:	https://doi.org/10.32598/ijmtfm.v11i3.33633 https://doaj.org/article/6ba8e8a2dbfb4c8c8786c2fe0772c1ef
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:6ba8e8a2dbfb4c8c8786c2fe0772c1ef
record_format	dspace
spelling	oai:doaj.org-article:6ba8e8a2dbfb4c8c8786c2fe0772c1ef2021-11-08T11:47:57ZTherapeutic Strategies in Managing Acute Paraquat Poisoning: A Review Studyhttps://doi.org/10.32598/ijmtfm.v11i3.336332251-87622251-8770https://doaj.org/article/6ba8e8a2dbfb4c8c8786c2fe0772c1ef2021-08-01T00:00:00Zhttps://journals.sbmu.ac.ir/ijmtfm/article/view/33633https://doaj.org/toc/2251-8762https://doaj.org/toc/2251-8770Background: Paraquat is an extremely toxic herbicide that causes such severe adverse effects as acute lung injury, pulmonary fibrosis, metabolic acidosis, cardiogenic shock, acute renal failure, and even death. Regarding the high prevalence and mortality rate without a specific antidote in paraquat poisoning, we explored managing acute paraquat poisoning. Methods: In this study, required articles were searched using the following keywords: “paraquat poisoning” and “treatment” on an electronic database, such as Pubmed and Google Scholar from January 2013 to December 2020. Results: This article examined pharmacokinetic, clinical, and laboratory findings, complications, diagnosis, prognostic factors, and the treatment of paraquat poisoning. Then, the medical management and therapeutic procedures of paraquat poisoning were discussed. Conclusion: Although there exists no antidote for paraquat poisoning, numerous therapeutic methods have been suggested for treating paraquat poisoning. However, their efficacy remains undiscovered. An interesting finding in one study indicating that endotracheal intubation is an inappropriate procedure for managing paraquat poisoning; further studies are required in this regard. For these reasons, preventing poisoning and using other herbicides with less toxicity than paraquat are recommended.Mohammad MajidiShaheed Beheshti University of Medical SciencesarticleherbicidesparaquatpoisoningtherapeuticsMedicine (General)R5-920Toxicology. PoisonsRA1190-1270ENInternational Journal of Medical Toxicology and Forensic Medicine, Vol 11, Iss 3, p 33633 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	herbicides paraquat poisoning therapeutics Medicine (General) R5-920 Toxicology. Poisons RA1190-1270
spellingShingle	herbicides paraquat poisoning therapeutics Medicine (General) R5-920 Toxicology. Poisons RA1190-1270 Mohammad Majidi Therapeutic Strategies in Managing Acute Paraquat Poisoning: A Review Study
description	Background: Paraquat is an extremely toxic herbicide that causes such severe adverse effects as acute lung injury, pulmonary fibrosis, metabolic acidosis, cardiogenic shock, acute renal failure, and even death. Regarding the high prevalence and mortality rate without a specific antidote in paraquat poisoning, we explored managing acute paraquat poisoning. Methods: In this study, required articles were searched using the following keywords: “paraquat poisoning” and “treatment” on an electronic database, such as Pubmed and Google Scholar from January 2013 to December 2020. Results: This article examined pharmacokinetic, clinical, and laboratory findings, complications, diagnosis, prognostic factors, and the treatment of paraquat poisoning. Then, the medical management and therapeutic procedures of paraquat poisoning were discussed. Conclusion: Although there exists no antidote for paraquat poisoning, numerous therapeutic methods have been suggested for treating paraquat poisoning. However, their efficacy remains undiscovered. An interesting finding in one study indicating that endotracheal intubation is an inappropriate procedure for managing paraquat poisoning; further studies are required in this regard. For these reasons, preventing poisoning and using other herbicides with less toxicity than paraquat are recommended.
format	article
author	Mohammad Majidi
author_facet	Mohammad Majidi
author_sort	Mohammad Majidi
title	Therapeutic Strategies in Managing Acute Paraquat Poisoning: A Review Study
title_short	Therapeutic Strategies in Managing Acute Paraquat Poisoning: A Review Study
title_full	Therapeutic Strategies in Managing Acute Paraquat Poisoning: A Review Study
title_fullStr	Therapeutic Strategies in Managing Acute Paraquat Poisoning: A Review Study
title_full_unstemmed	Therapeutic Strategies in Managing Acute Paraquat Poisoning: A Review Study
title_sort	therapeutic strategies in managing acute paraquat poisoning: a review study
publisher	Shaheed Beheshti University of Medical Sciences
publishDate	2021
url	https://doi.org/10.32598/ijmtfm.v11i3.33633 https://doaj.org/article/6ba8e8a2dbfb4c8c8786c2fe0772c1ef
work_keys_str_mv	AT mohammadmajidi therapeuticstrategiesinmanagingacuteparaquatpoisoningareviewstudy
_version_	1718442245546311680

Therapeutic Strategies in Managing Acute Paraquat Poisoning: A Review Study

Ejemplares similares