Transcriptomic analysis identifies differences in gene expression in actinic keratoses after treatment with imiquimod and between responders and non responders

Transcriptomic analysis identifies differences in gene expression in actinic keratoses after treatment with imiquimod and between responders and non responders

Abstract The presence of actinic keratoses (AKs) increases a patient’s risk of developing squamous cell carcinoma by greater than six-fold. We evaluated the effect of topical treatment with imiquimod on the tumor microenvironment by measuring transcriptomic differences in AKs before and after treatm...

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Autores principales: Megan H. Trager, Emanuelle Rizk, Sharon Rose, Kuixi Zhu, Branden Lau, Benjamin T. Fullerton, Jaya Pradhan, Michael Moore, Ayush C. Srivastava, Giselle Singer, Robyn Gartrell, Rui Chang, Larisa J. Geskin, Yvonne M. Saenger, Gary Goldenberg
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
Materias:
Medicine
R
Science
Q
Acceso en línea:https://doaj.org/article/6bb5791204724714b50998aaf52add66
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