PKA drives an increase in AMPA receptor unitary conductance during LTP in the hippocampus

Long-term potentiation at hippocampal CA1 synapses can be due to increasing the number and/or single-channel conductance of AMPA receptors. The authors show that PKA and CaMKII are necessary and together sufficient to increase single channel conductance, via insertion of calcium-permeable AMPA recep...

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Autores principales:	Pojeong Park, John Georgiou, Thomas M. Sanderson, Kwang-Hee Ko, Heather Kang, Ji-il Kim, Clarrisa A. Bradley, Zuner A. Bortolotto, Min Zhuo, Bong-Kiun Kaang, Graham L. Collingridge
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/6bc2d2a14d284ff78483650a8ff577eb
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spelling	oai:doaj.org-article:6bc2d2a14d284ff78483650a8ff577eb2021-12-02T14:19:04ZPKA drives an increase in AMPA receptor unitary conductance during LTP in the hippocampus10.1038/s41467-020-20523-32041-1723https://doaj.org/article/6bc2d2a14d284ff78483650a8ff577eb2021-01-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-20523-3https://doaj.org/toc/2041-1723Long-term potentiation at hippocampal CA1 synapses can be due to increasing the number and/or single-channel conductance of AMPA receptors. The authors show that PKA and CaMKII are necessary and together sufficient to increase single channel conductance, via insertion of calcium-permeable AMPA receptors.Pojeong ParkJohn GeorgiouThomas M. SandersonKwang-Hee KoHeather KangJi-il KimClarrisa A. BradleyZuner A. BortolottoMin ZhuoBong-Kiun KaangGraham L. CollingridgeNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-15 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Pojeong Park John Georgiou Thomas M. Sanderson Kwang-Hee Ko Heather Kang Ji-il Kim Clarrisa A. Bradley Zuner A. Bortolotto Min Zhuo Bong-Kiun Kaang Graham L. Collingridge PKA drives an increase in AMPA receptor unitary conductance during LTP in the hippocampus
description	Long-term potentiation at hippocampal CA1 synapses can be due to increasing the number and/or single-channel conductance of AMPA receptors. The authors show that PKA and CaMKII are necessary and together sufficient to increase single channel conductance, via insertion of calcium-permeable AMPA receptors.
format	article
author	Pojeong Park John Georgiou Thomas M. Sanderson Kwang-Hee Ko Heather Kang Ji-il Kim Clarrisa A. Bradley Zuner A. Bortolotto Min Zhuo Bong-Kiun Kaang Graham L. Collingridge
author_facet	Pojeong Park John Georgiou Thomas M. Sanderson Kwang-Hee Ko Heather Kang Ji-il Kim Clarrisa A. Bradley Zuner A. Bortolotto Min Zhuo Bong-Kiun Kaang Graham L. Collingridge
author_sort	Pojeong Park
title	PKA drives an increase in AMPA receptor unitary conductance during LTP in the hippocampus
title_short	PKA drives an increase in AMPA receptor unitary conductance during LTP in the hippocampus
title_full	PKA drives an increase in AMPA receptor unitary conductance during LTP in the hippocampus
title_fullStr	PKA drives an increase in AMPA receptor unitary conductance during LTP in the hippocampus
title_full_unstemmed	PKA drives an increase in AMPA receptor unitary conductance during LTP in the hippocampus
title_sort	pka drives an increase in ampa receptor unitary conductance during ltp in the hippocampus
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/6bc2d2a14d284ff78483650a8ff577eb
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PKA drives an increase in AMPA receptor unitary conductance during LTP in the hippocampus

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