The prevalence of human immunodeficiency virus infection among TB patients in Port Harcourt Nigeria

O Erhabor1, Z A Jeremiah2, T C Adias1, Okere CE21Department of Medical Laboratory Sciences, College of Health Sciences, Niger Delta University, Wilbeforce Island, Bayelsa State, Nigeria; 2Department of Medical Laboratory Sciences, Rivers State University of Science and Technology, Port Harcourt, Nig...

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Autores principales:	O Erhabor, Z A Jeremiah, T C Adias, et al
Formato:	article
Lenguaje:	EN
Publicado:	Dove Medical Press 2010
Materias:	Immunologic diseases. Allergy RC581-607
Acceso en línea:	https://doaj.org/article/6bc850cb2db2488785ada71c7853cd47
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spelling	oai:doaj.org-article:6bc850cb2db2488785ada71c7853cd472021-12-02T01:11:57ZThe prevalence of human immunodeficiency virus infection among TB patients in Port Harcourt Nigeria1179-1373https://doaj.org/article/6bc850cb2db2488785ada71c7853cd472010-01-01T00:00:00Zhttp://www.dovepress.com/the-prevalence-of-human-immunodeficiency-virus-infection-among-tb-pati-a3902https://doaj.org/toc/1179-1373O Erhabor1, Z A Jeremiah2, T C Adias1, Okere CE21Department of Medical Laboratory Sciences, College of Health Sciences, Niger Delta University, Wilbeforce Island, Bayelsa State, Nigeria; 2Department of Medical Laboratory Sciences, Rivers State University of Science and Technology, Port Harcourt, NigeriaAbstract: The joint statement by the American Thoracic Society, Centers for Disease Control and Prevention, and Infectious Diseases Society of America recommends that all patients with tuberculosis (TB) undergo testing for human immunodeficiency virus (HIV) infection after counseling. In this study, we investigated the prevalence of HIV infection among 120 patients diagnosed with microbiologically proven TB aged 18 to 54 years with a mean age of 39.5 years (standard deviation 6.75). The subjects studied were 36 male (30%) and 84 females (70%). Enzyme-linked immunosorbent assay methods were used to screen for HIV infection among the subjects. Of the 120 TB patients tested 30 (25%) were positive for HIV infection. The prevalence of HIV was higher in females 24 (80%) compared to males 6 (20%) and among singles (66.7%) compared to married subjects (33.3%) (&chi;2 = 83.5 and &chi;2 = 126.2, respectively P = 0.001). HIV-1 was the predominant viral subtype. HIV prevalence was significantly higher in subjects in the 38&ndash;47 year and 28&ndash;37 year age groups (both 40%) followed by the 18&ndash;28 year age group (20%) (&chi;2 = 42.6, P = 0.05). The mean CD4 lymphocyte count of the HIV-infected TB subjects was significantly lower (195 &plusmn; 40.5 cells/&mu;L) compared to the non-HIV infected (288 &plusmn; 35.25 cells/&mu;L P = 0.01). This study has shown a high prevalence of HIV among TB patients. Reactivation of TB among people living with HIV can be reduced by TB preventive therapy and by universal access to antiretroviral therapy.Keywords: human immunodeficiency virus, HIV, acquired immunodeficiency syndrome AIDS, tuberculosis, TB, Port Harcourt, Nigeria O ErhaborZ A JeremiahT C Adiaset alDove Medical PressarticleImmunologic diseases. AllergyRC581-607ENHIV/AIDS: Research and Palliative Care, Vol 2010, Iss default, Pp 1-5 (2010)
institution	DOAJ
collection	DOAJ
language	EN
topic	Immunologic diseases. Allergy RC581-607
spellingShingle	Immunologic diseases. Allergy RC581-607 O Erhabor Z A Jeremiah T C Adias et al The prevalence of human immunodeficiency virus infection among TB patients in Port Harcourt Nigeria
description	O Erhabor1, Z A Jeremiah2, T C Adias1, Okere CE21Department of Medical Laboratory Sciences, College of Health Sciences, Niger Delta University, Wilbeforce Island, Bayelsa State, Nigeria; 2Department of Medical Laboratory Sciences, Rivers State University of Science and Technology, Port Harcourt, NigeriaAbstract: The joint statement by the American Thoracic Society, Centers for Disease Control and Prevention, and Infectious Diseases Society of America recommends that all patients with tuberculosis (TB) undergo testing for human immunodeficiency virus (HIV) infection after counseling. In this study, we investigated the prevalence of HIV infection among 120 patients diagnosed with microbiologically proven TB aged 18 to 54 years with a mean age of 39.5 years (standard deviation 6.75). The subjects studied were 36 male (30%) and 84 females (70%). Enzyme-linked immunosorbent assay methods were used to screen for HIV infection among the subjects. Of the 120 TB patients tested 30 (25%) were positive for HIV infection. The prevalence of HIV was higher in females 24 (80%) compared to males 6 (20%) and among singles (66.7%) compared to married subjects (33.3%) (&chi;2 = 83.5 and &chi;2 = 126.2, respectively P = 0.001). HIV-1 was the predominant viral subtype. HIV prevalence was significantly higher in subjects in the 38&ndash;47 year and 28&ndash;37 year age groups (both 40%) followed by the 18&ndash;28 year age group (20%) (&chi;2 = 42.6, P = 0.05). The mean CD4 lymphocyte count of the HIV-infected TB subjects was significantly lower (195 &plusmn; 40.5 cells/&mu;L) compared to the non-HIV infected (288 &plusmn; 35.25 cells/&mu;L P = 0.01). This study has shown a high prevalence of HIV among TB patients. Reactivation of TB among people living with HIV can be reduced by TB preventive therapy and by universal access to antiretroviral therapy.Keywords: human immunodeficiency virus, HIV, acquired immunodeficiency syndrome AIDS, tuberculosis, TB, Port Harcourt, Nigeria
format	article
author	O Erhabor Z A Jeremiah T C Adias et al
author_facet	O Erhabor Z A Jeremiah T C Adias et al
author_sort	O Erhabor
title	The prevalence of human immunodeficiency virus infection among TB patients in Port Harcourt Nigeria
title_short	The prevalence of human immunodeficiency virus infection among TB patients in Port Harcourt Nigeria
title_full	The prevalence of human immunodeficiency virus infection among TB patients in Port Harcourt Nigeria
title_fullStr	The prevalence of human immunodeficiency virus infection among TB patients in Port Harcourt Nigeria
title_full_unstemmed	The prevalence of human immunodeficiency virus infection among TB patients in Port Harcourt Nigeria
title_sort	prevalence of human immunodeficiency virus infection among tb patients in port harcourt nigeria
publisher	Dove Medical Press
publishDate	2010
url	https://doaj.org/article/6bc850cb2db2488785ada71c7853cd47
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The prevalence of human immunodeficiency virus infection among TB patients in Port Harcourt Nigeria

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