Early overnutrition sensitizes the growth hormone axis to the impact of diet-induced obesity via sex-divergent mechanisms

Abstract In addition to its essential role in the physiological control of longitudinal growth, growth-hormone (GH) is endowed with relevant metabolic functions, including anabolic actions in muscle, lipolysis in adipose-tissue and glycemic modulation. Adult obesity is known to negatively impact GH-...

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Auteurs principaux: M. A. Sanchez-Garrido, F. Ruiz-Pino, A. I. Pozo-Salas, J. M. Castellano, M. J. Vazquez, R. M. Luque, M. Tena-Sempere
Format: article
Langue:EN
Publié: Nature Portfolio 2020
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Accès en ligne:https://doaj.org/article/6bcb8423bb8f4653824e48cf7cce764b
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