Clinical utility of implantable neurostimulation devices in the treatment of chronic migraine

John A Freeman, Terrance L Trentman Department of Anesthesiology, Division of Pain Medicine, Mayo Clinic Arizona, Phoenix, AZ, USA Abstract: Chronic migraine is a disabling disorder that is costly to individuals and society. Occipital nerve stimulation has been used to treat refractory cases of prim...

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Autores principales: Freeman JA, Trentman TL
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Lenguaje:EN
Publicado: Dove Medical Press 2013
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Acceso en línea:https://doaj.org/article/6bd46b8679004de39f4c5918d61acc51
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spelling oai:doaj.org-article:6bd46b8679004de39f4c5918d61acc512021-12-02T03:44:20ZClinical utility of implantable neurostimulation devices in the treatment of chronic migraine1179-1470https://doaj.org/article/6bd46b8679004de39f4c5918d61acc512013-11-01T00:00:00Zhttp://www.dovepress.com/clinical-utility-of-implantable-neurostimulation-devices-in-the-treatm-a15031https://doaj.org/toc/1179-1470John A Freeman, Terrance L Trentman Department of Anesthesiology, Division of Pain Medicine, Mayo Clinic Arizona, Phoenix, AZ, USA Abstract: Chronic migraine is a disabling disorder that is costly to individuals and society. Occipital nerve stimulation has been used to treat refractory cases of primary headache disorders including drug-resistant chronic cluster headaches and chronic migraine. The Food and Drug Administration (FDA) off-labeled application of equipment used for peripheral nerve (occipital) stimulation is borrowed from FDA-labeled spinal cord stimulation. Manufacturer-sponsored randomized trials include a feasibility study (ONSTIM-Medtronic) and a safety and efficacy study (St Jude). A non-industry sponsored prospective, randomized crossover study by Serra and Marchiotretto suggests improved quality of life and a significant reduction in medication use. Though preliminary studies suggest occipital nerve stimulation is safe and efficacious in treating chronic migraine headache, complication rates, including lead migration, lead fracture, and surgical site infections remain high. Further studies are needed to demonstrate long-term outcomes, while improved surgical techniques and site-specific equipment are needed to minimize complications. Keywords: headache, occipital nerve stimulation, peripheral nerve stimulation, neuromodulation, electrical stimulation therapyFreeman JATrentman TLDove Medical PressarticleMedical technologyR855-855.5ENMedical Devices: Evidence and Research, Vol 2013, Iss default, Pp 195-201 (2013)
institution DOAJ
collection DOAJ
language EN
topic Medical technology
R855-855.5
spellingShingle Medical technology
R855-855.5
Freeman JA
Trentman TL
Clinical utility of implantable neurostimulation devices in the treatment of chronic migraine
description John A Freeman, Terrance L Trentman Department of Anesthesiology, Division of Pain Medicine, Mayo Clinic Arizona, Phoenix, AZ, USA Abstract: Chronic migraine is a disabling disorder that is costly to individuals and society. Occipital nerve stimulation has been used to treat refractory cases of primary headache disorders including drug-resistant chronic cluster headaches and chronic migraine. The Food and Drug Administration (FDA) off-labeled application of equipment used for peripheral nerve (occipital) stimulation is borrowed from FDA-labeled spinal cord stimulation. Manufacturer-sponsored randomized trials include a feasibility study (ONSTIM-Medtronic) and a safety and efficacy study (St Jude). A non-industry sponsored prospective, randomized crossover study by Serra and Marchiotretto suggests improved quality of life and a significant reduction in medication use. Though preliminary studies suggest occipital nerve stimulation is safe and efficacious in treating chronic migraine headache, complication rates, including lead migration, lead fracture, and surgical site infections remain high. Further studies are needed to demonstrate long-term outcomes, while improved surgical techniques and site-specific equipment are needed to minimize complications. Keywords: headache, occipital nerve stimulation, peripheral nerve stimulation, neuromodulation, electrical stimulation therapy
format article
author Freeman JA
Trentman TL
author_facet Freeman JA
Trentman TL
author_sort Freeman JA
title Clinical utility of implantable neurostimulation devices in the treatment of chronic migraine
title_short Clinical utility of implantable neurostimulation devices in the treatment of chronic migraine
title_full Clinical utility of implantable neurostimulation devices in the treatment of chronic migraine
title_fullStr Clinical utility of implantable neurostimulation devices in the treatment of chronic migraine
title_full_unstemmed Clinical utility of implantable neurostimulation devices in the treatment of chronic migraine
title_sort clinical utility of implantable neurostimulation devices in the treatment of chronic migraine
publisher Dove Medical Press
publishDate 2013
url https://doaj.org/article/6bd46b8679004de39f4c5918d61acc51
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