Transcriptome analyses of inhibitor-treated schistosome females provide evidence for cooperating Src-kinase and TGFβ receptor pathways controlling mitosis and eggshell formation.

Schistosome parasites cause schistosomiasis, one of the most prevalent parasitemias worldwide affecting humans and animals. Constant pairing of schistosomes is essential for female sexual maturation and egg production, which causes pathogenesis. Female maturation involves signaling pathways controll...

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Autores principales: Christin Buro, Katia C Oliveira, Zhigang Lu, Silke Leutner, Svenja Beckmann, Colette Dissous, Katia Cailliau, Sergio Verjovski-Almeida, Christoph G Grevelding
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2013
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Acceso en línea:https://doaj.org/article/6bd9a8d20fe3409d9d9d9a5d70aae4c1
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