Clinical and Epidemiological Characteristics of 1283 Pediatric Patients with Coronavirus Disease 2019 during the First and Second Waves of the Pandemic—Results of the Pediatric Part of a Multicenter Polish Register SARSTer
This prospective multicenter cohort study aimed to analyze the epidemiological and clinical characteristics of coronavirus disease 2019 (COVID-19) in children. The study, based on the pediatric part of the Polish SARSTer register, included 1283 children (0 to 18 years) who were diagnosed with COVID-...
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oai:doaj.org-article:6bddbc4d831f4d00ae728cbdba62d9942021-11-11T17:43:20ZClinical and Epidemiological Characteristics of 1283 Pediatric Patients with Coronavirus Disease 2019 during the First and Second Waves of the Pandemic—Results of the Pediatric Part of a Multicenter Polish Register SARSTer10.3390/jcm102150982077-0383https://doaj.org/article/6bddbc4d831f4d00ae728cbdba62d9942021-10-01T00:00:00Zhttps://www.mdpi.com/2077-0383/10/21/5098https://doaj.org/toc/2077-0383This prospective multicenter cohort study aimed to analyze the epidemiological and clinical characteristics of coronavirus disease 2019 (COVID-19) in children. The study, based on the pediatric part of the Polish SARSTer register, included 1283 children (0 to 18 years) who were diagnosed with COVID-19 between 1 March 2020 and 31 December 2020. Household contact was reported in 56% of cases, more frequently in younger children. Fever was the most common symptom (46%). The youngest children (0–5 years) more frequently presented with fever, rhinitis and diarrhea. Teenagers more often complained of headache, sore throat, anosmia/ageusia and weakness. One fifth of patients were reported to be asymptomatic. Pneumonia was diagnosed in 12% of patients, more frequently in younger children. During the second wave patients were younger than during the first wave (median age 53 vs. 102 months, <i>p</i> < 0.0001) and required longer hospitalization (<i>p</i> < 0.0001). Significantly fewer asymptomatic patients were noted and pneumonia as well as gastrointestinal symptoms were more common. The epidemiological characteristics of pediatric patients and the clinical presentation of COVID-19 are age-related. Younger children were more frequently infected by close relatives, more often suffered from pneumonia and gastrointestinal symptoms and required hospitalization. Clinical courses differed significantly during the first two waves of the pandemic.Maria Pokorska-ŚpiewakEwa TalarekAnna ManiaMałgorzata PawłowskaJolanta PopielskaKonrad ZawadkaMagdalena FiglerowiczKatarzyna Mazur-MelewskaKamil FaltinPrzemysław CiechanowskiJoanna Łasecka-ZadrożnaJózef RudnickiBarbara HasiecMartyna StaniPaulina Frańczak-ChmuraIzabela ZaleskaLeszek SzenbornKacper ToczyłowskiArtur SulikBarbara SzczepańskaIlona Pałyga-BysieckaIzabela KucharekAdam SybilskiMałgorzata Sobolewska-PilarczykUrszula DryjaEwa Majda-StanisławskaSławomira NiedźwieckaErnest KucharBolesław KalickiAnna GorczycaMagdalena MarczyńskaMDPI AGarticlechildrenclinical presentationcoronavirus disease 2019 (COVID-19)epidemiologysevere acute respiratory syndrome coronavirus 2 (SARS-CoV-2)MedicineRENJournal of Clinical Medicine, Vol 10, Iss 5098, p 5098 (2021) |
| institution |
DOAJ |
| collection |
DOAJ |
| language |
EN |
| topic |
children clinical presentation coronavirus disease 2019 (COVID-19) epidemiology severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Medicine R |
| spellingShingle |
children clinical presentation coronavirus disease 2019 (COVID-19) epidemiology severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Medicine R Maria Pokorska-Śpiewak Ewa Talarek Anna Mania Małgorzata Pawłowska Jolanta Popielska Konrad Zawadka Magdalena Figlerowicz Katarzyna Mazur-Melewska Kamil Faltin Przemysław Ciechanowski Joanna Łasecka-Zadrożna Józef Rudnicki Barbara Hasiec Martyna Stani Paulina Frańczak-Chmura Izabela Zaleska Leszek Szenborn Kacper Toczyłowski Artur Sulik Barbara Szczepańska Ilona Pałyga-Bysiecka Izabela Kucharek Adam Sybilski Małgorzata Sobolewska-Pilarczyk Urszula Dryja Ewa Majda-Stanisławska Sławomira Niedźwiecka Ernest Kuchar Bolesław Kalicki Anna Gorczyca Magdalena Marczyńska Clinical and Epidemiological Characteristics of 1283 Pediatric Patients with Coronavirus Disease 2019 during the First and Second Waves of the Pandemic—Results of the Pediatric Part of a Multicenter Polish Register SARSTer |
| description |
This prospective multicenter cohort study aimed to analyze the epidemiological and clinical characteristics of coronavirus disease 2019 (COVID-19) in children. The study, based on the pediatric part of the Polish SARSTer register, included 1283 children (0 to 18 years) who were diagnosed with COVID-19 between 1 March 2020 and 31 December 2020. Household contact was reported in 56% of cases, more frequently in younger children. Fever was the most common symptom (46%). The youngest children (0–5 years) more frequently presented with fever, rhinitis and diarrhea. Teenagers more often complained of headache, sore throat, anosmia/ageusia and weakness. One fifth of patients were reported to be asymptomatic. Pneumonia was diagnosed in 12% of patients, more frequently in younger children. During the second wave patients were younger than during the first wave (median age 53 vs. 102 months, <i>p</i> < 0.0001) and required longer hospitalization (<i>p</i> < 0.0001). Significantly fewer asymptomatic patients were noted and pneumonia as well as gastrointestinal symptoms were more common. The epidemiological characteristics of pediatric patients and the clinical presentation of COVID-19 are age-related. Younger children were more frequently infected by close relatives, more often suffered from pneumonia and gastrointestinal symptoms and required hospitalization. Clinical courses differed significantly during the first two waves of the pandemic. |
| format |
article |
| author |
Maria Pokorska-Śpiewak Ewa Talarek Anna Mania Małgorzata Pawłowska Jolanta Popielska Konrad Zawadka Magdalena Figlerowicz Katarzyna Mazur-Melewska Kamil Faltin Przemysław Ciechanowski Joanna Łasecka-Zadrożna Józef Rudnicki Barbara Hasiec Martyna Stani Paulina Frańczak-Chmura Izabela Zaleska Leszek Szenborn Kacper Toczyłowski Artur Sulik Barbara Szczepańska Ilona Pałyga-Bysiecka Izabela Kucharek Adam Sybilski Małgorzata Sobolewska-Pilarczyk Urszula Dryja Ewa Majda-Stanisławska Sławomira Niedźwiecka Ernest Kuchar Bolesław Kalicki Anna Gorczyca Magdalena Marczyńska |
| author_facet |
Maria Pokorska-Śpiewak Ewa Talarek Anna Mania Małgorzata Pawłowska Jolanta Popielska Konrad Zawadka Magdalena Figlerowicz Katarzyna Mazur-Melewska Kamil Faltin Przemysław Ciechanowski Joanna Łasecka-Zadrożna Józef Rudnicki Barbara Hasiec Martyna Stani Paulina Frańczak-Chmura Izabela Zaleska Leszek Szenborn Kacper Toczyłowski Artur Sulik Barbara Szczepańska Ilona Pałyga-Bysiecka Izabela Kucharek Adam Sybilski Małgorzata Sobolewska-Pilarczyk Urszula Dryja Ewa Majda-Stanisławska Sławomira Niedźwiecka Ernest Kuchar Bolesław Kalicki Anna Gorczyca Magdalena Marczyńska |
| author_sort |
Maria Pokorska-Śpiewak |
| title |
Clinical and Epidemiological Characteristics of 1283 Pediatric Patients with Coronavirus Disease 2019 during the First and Second Waves of the Pandemic—Results of the Pediatric Part of a Multicenter Polish Register SARSTer |
| title_short |
Clinical and Epidemiological Characteristics of 1283 Pediatric Patients with Coronavirus Disease 2019 during the First and Second Waves of the Pandemic—Results of the Pediatric Part of a Multicenter Polish Register SARSTer |
| title_full |
Clinical and Epidemiological Characteristics of 1283 Pediatric Patients with Coronavirus Disease 2019 during the First and Second Waves of the Pandemic—Results of the Pediatric Part of a Multicenter Polish Register SARSTer |
| title_fullStr |
Clinical and Epidemiological Characteristics of 1283 Pediatric Patients with Coronavirus Disease 2019 during the First and Second Waves of the Pandemic—Results of the Pediatric Part of a Multicenter Polish Register SARSTer |
| title_full_unstemmed |
Clinical and Epidemiological Characteristics of 1283 Pediatric Patients with Coronavirus Disease 2019 during the First and Second Waves of the Pandemic—Results of the Pediatric Part of a Multicenter Polish Register SARSTer |
| title_sort |
clinical and epidemiological characteristics of 1283 pediatric patients with coronavirus disease 2019 during the first and second waves of the pandemic—results of the pediatric part of a multicenter polish register sarster |
| publisher |
MDPI AG |
| publishDate |
2021 |
| url |
https://doaj.org/article/6bddbc4d831f4d00ae728cbdba62d994 |
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