Monomeric ephrinB2 binding induces allosteric changes in Nipah virus G that precede its full activation

Nipah virus causes encephalitis in humans. Here the authors use a multidisciplinary approach to study the binding of the viral attachment protein G to its host receptor ephrinB2 and show that monomeric and dimeric receptors activate distinct conformational changes in G and discuss implications for r...

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Auteurs principaux: Joyce J. W. Wong, Tracy A. Young, Jiayan Zhang, Shiheng Liu, George P. Leser, Elizabeth A. Komives, Robert A. Lamb, Z. Hong Zhou, Joshua Salafsky, Theodore S. Jardetzky
Format: article
Langue:EN
Publié: Nature Portfolio 2017
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Accès en ligne:https://doaj.org/article/6bf2cd0a2e484c86a8eb86d2ea0a7ae4
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