Lybatides from Lycium barbarum Contain An Unusual Cystine-stapled Helical Peptide Scaffold

Lybatides from Lycium barbarum Contain An Unusual Cystine-stapled Helical Peptide Scaffold

Abstract Cysteine-rich peptides (CRPs) of 2–6 kDa are generally thermally and proteolytically stable because of their multiple cross-bracing disulfide bonds. Here, we report the discovery and characterization of two novel cystine-stapled CRPs, designated lybatide 1 and 2 (lyba1 and lyba2), from the...

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Autores principales: Wei Liang Tan, Ka H. Wong, Jian Lei, Naoki Sakai, Hong Wei Tan, Rolf Hilgenfeld, James P. Tam
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2017
Materias:
Medicine
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Science
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Acceso en línea:https://doaj.org/article/6bf374fb01a84458acc00e754ce89c4c
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