MAPCap allows high-resolution detection and differential expression analysis of transcription start sites

The position, shape and number of transcription start sites (TSS) regulate gene expression. Here authors present MAPCap, a method for high-resolution detection and differential expression analysis of TSS, and apply MAPCap to early fly development, detecting stage and sex-specific promoter and enhanc...

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Autores principales: Vivek Bhardwaj, Giuseppe Semplicio, Niyazi Umut Erdogdu, Thomas Manke, Asifa Akhtar
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2019
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Acceso en línea:https://doaj.org/article/6bf4f34d86bc45989b2c72fd98afe691
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spelling oai:doaj.org-article:6bf4f34d86bc45989b2c72fd98afe6912021-12-02T17:01:34ZMAPCap allows high-resolution detection and differential expression analysis of transcription start sites10.1038/s41467-019-11115-x2041-1723https://doaj.org/article/6bf4f34d86bc45989b2c72fd98afe6912019-07-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-11115-xhttps://doaj.org/toc/2041-1723The position, shape and number of transcription start sites (TSS) regulate gene expression. Here authors present MAPCap, a method for high-resolution detection and differential expression analysis of TSS, and apply MAPCap to early fly development, detecting stage and sex-specific promoter and enhancer activity.Vivek BhardwajGiuseppe SemplicioNiyazi Umut ErdogduThomas MankeAsifa AkhtarNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-15 (2019)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Vivek Bhardwaj
Giuseppe Semplicio
Niyazi Umut Erdogdu
Thomas Manke
Asifa Akhtar
MAPCap allows high-resolution detection and differential expression analysis of transcription start sites
description The position, shape and number of transcription start sites (TSS) regulate gene expression. Here authors present MAPCap, a method for high-resolution detection and differential expression analysis of TSS, and apply MAPCap to early fly development, detecting stage and sex-specific promoter and enhancer activity.
format article
author Vivek Bhardwaj
Giuseppe Semplicio
Niyazi Umut Erdogdu
Thomas Manke
Asifa Akhtar
author_facet Vivek Bhardwaj
Giuseppe Semplicio
Niyazi Umut Erdogdu
Thomas Manke
Asifa Akhtar
author_sort Vivek Bhardwaj
title MAPCap allows high-resolution detection and differential expression analysis of transcription start sites
title_short MAPCap allows high-resolution detection and differential expression analysis of transcription start sites
title_full MAPCap allows high-resolution detection and differential expression analysis of transcription start sites
title_fullStr MAPCap allows high-resolution detection and differential expression analysis of transcription start sites
title_full_unstemmed MAPCap allows high-resolution detection and differential expression analysis of transcription start sites
title_sort mapcap allows high-resolution detection and differential expression analysis of transcription start sites
publisher Nature Portfolio
publishDate 2019
url https://doaj.org/article/6bf4f34d86bc45989b2c72fd98afe691
work_keys_str_mv AT vivekbhardwaj mapcapallowshighresolutiondetectionanddifferentialexpressionanalysisoftranscriptionstartsites
AT giuseppesemplicio mapcapallowshighresolutiondetectionanddifferentialexpressionanalysisoftranscriptionstartsites
AT niyaziumuterdogdu mapcapallowshighresolutiondetectionanddifferentialexpressionanalysisoftranscriptionstartsites
AT thomasmanke mapcapallowshighresolutiondetectionanddifferentialexpressionanalysisoftranscriptionstartsites
AT asifaakhtar mapcapallowshighresolutiondetectionanddifferentialexpressionanalysisoftranscriptionstartsites
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