DNA methylation and Transcriptome Changes Associated with Cisplatin Resistance in Ovarian Cancer

DNA methylation and Transcriptome Changes Associated with Cisplatin Resistance in Ovarian Cancer

Abstract High-grade serous ovarian cancer is the most common ovarian cancer type. Although the combination of surgery and platinum-taxane chemotherapy provide an effective treatment, drug resistance frequently occurs leading to poor outcome. In order to clarify the molecular mechanisms of drug resis...

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Autores principales: Riikka J. Lund, Kaisa Huhtinen, Jussi Salmi, Juha Rantala, Elizabeth V. Nguyen, Robert Moulder, David R. Goodlett, Riitta Lahesmaa, Olli Carpén
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2017
Materias:
Medicine
R
Science
Q
Acceso en línea:https://doaj.org/article/6c01c760084d476eacca4d213f37d8c8
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