Incidence and risk factors analysis for mortality after total knee arthroplasty based on a large national database in Korea

Abstract This study aimed to analyze the rates and risk factors of postoperative mortality among 560,954 patients who underwent total knee arthroplasty (TKA) in Korea. The National Health Insurance Service-Health Screening database was used to analyze 560,954 patients who underwent TKA between 2005...

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Autores principales:	Ho-Jun Choi, Han-Kook Yoon, Hyun-Cheol Oh, Ju-Hyung Yoo, Chong-Hyuk Choi, Jin-Ho Lee, Sang-Hoon Park
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Medicine R Science Q
Acceso en línea:	https://doaj.org/article/6c0bcd9e0c664fa383e66b7cb1adfac4
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spelling	oai:doaj.org-article:6c0bcd9e0c664fa383e66b7cb1adfac42021-12-02T16:35:27ZIncidence and risk factors analysis for mortality after total knee arthroplasty based on a large national database in Korea10.1038/s41598-021-95346-32045-2322https://doaj.org/article/6c0bcd9e0c664fa383e66b7cb1adfac42021-08-01T00:00:00Zhttps://doi.org/10.1038/s41598-021-95346-3https://doaj.org/toc/2045-2322Abstract This study aimed to analyze the rates and risk factors of postoperative mortality among 560,954 patients who underwent total knee arthroplasty (TKA) in Korea. The National Health Insurance Service-Health Screening database was used to analyze 560,954 patients who underwent TKA between 2005 and 2018. In-hospital, ninety-day, and one-year postoperative mortality, and their association with patient’s demographic factors and various comorbidities (ie., cerebrovascular disease, congestive heart failure, and myocardial infarction) were assessed. In-hospital, ninety-day and one-year mortality rates after TKA were similar from 2005 to 2018. The risk of in-hospital mortality increased with comorbidities like cerebrovascular disease (hazard ratio [HR] = 1.401; 95% confidence interval [CI] = 1.064–1.844), congestive heart failure (HR = 2.004; 95% CI = 1.394 to 2.881), myocardial infarction (HR = 2.111; 95% CI = 1.115 to 3.998), and renal disease (HR = 2.641; 95% CI = 1.348–5.173). These co-morbidities were also independent predictors of ninety-day and one-year mortality. Male sex and old age were independent predictors for ninety-day and one-year mortality. And malignancy was risk factor for one-year mortality. The common preoperative risk factors for mortality in all periods were male sex, old age, cerebrovascular disease, congestive heart failure, myocardial infarction, and renal disease. Malignancy was identified as risk factor for one-year mortality. Patients with these comorbidities should be provided better perioperative care.Ho-Jun ChoiHan-Kook YoonHyun-Cheol OhJu-Hyung YooChong-Hyuk ChoiJin-Ho LeeSang-Hoon ParkNature PortfolioarticleMedicineRScienceQENScientific Reports, Vol 11, Iss 1, Pp 1-9 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine R Science Q
spellingShingle	Medicine R Science Q Ho-Jun Choi Han-Kook Yoon Hyun-Cheol Oh Ju-Hyung Yoo Chong-Hyuk Choi Jin-Ho Lee Sang-Hoon Park Incidence and risk factors analysis for mortality after total knee arthroplasty based on a large national database in Korea
description	Abstract This study aimed to analyze the rates and risk factors of postoperative mortality among 560,954 patients who underwent total knee arthroplasty (TKA) in Korea. The National Health Insurance Service-Health Screening database was used to analyze 560,954 patients who underwent TKA between 2005 and 2018. In-hospital, ninety-day, and one-year postoperative mortality, and their association with patient’s demographic factors and various comorbidities (ie., cerebrovascular disease, congestive heart failure, and myocardial infarction) were assessed. In-hospital, ninety-day and one-year mortality rates after TKA were similar from 2005 to 2018. The risk of in-hospital mortality increased with comorbidities like cerebrovascular disease (hazard ratio [HR] = 1.401; 95% confidence interval [CI] = 1.064–1.844), congestive heart failure (HR = 2.004; 95% CI = 1.394 to 2.881), myocardial infarction (HR = 2.111; 95% CI = 1.115 to 3.998), and renal disease (HR = 2.641; 95% CI = 1.348–5.173). These co-morbidities were also independent predictors of ninety-day and one-year mortality. Male sex and old age were independent predictors for ninety-day and one-year mortality. And malignancy was risk factor for one-year mortality. The common preoperative risk factors for mortality in all periods were male sex, old age, cerebrovascular disease, congestive heart failure, myocardial infarction, and renal disease. Malignancy was identified as risk factor for one-year mortality. Patients with these comorbidities should be provided better perioperative care.
format	article
author	Ho-Jun Choi Han-Kook Yoon Hyun-Cheol Oh Ju-Hyung Yoo Chong-Hyuk Choi Jin-Ho Lee Sang-Hoon Park
author_facet	Ho-Jun Choi Han-Kook Yoon Hyun-Cheol Oh Ju-Hyung Yoo Chong-Hyuk Choi Jin-Ho Lee Sang-Hoon Park
author_sort	Ho-Jun Choi
title	Incidence and risk factors analysis for mortality after total knee arthroplasty based on a large national database in Korea
title_short	Incidence and risk factors analysis for mortality after total knee arthroplasty based on a large national database in Korea
title_full	Incidence and risk factors analysis for mortality after total knee arthroplasty based on a large national database in Korea
title_fullStr	Incidence and risk factors analysis for mortality after total knee arthroplasty based on a large national database in Korea
title_full_unstemmed	Incidence and risk factors analysis for mortality after total knee arthroplasty based on a large national database in Korea
title_sort	incidence and risk factors analysis for mortality after total knee arthroplasty based on a large national database in korea
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/6c0bcd9e0c664fa383e66b7cb1adfac4
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_version_	1718383695302230016

Incidence and risk factors analysis for mortality after total knee arthroplasty based on a large national database in Korea

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