IFITM3 Reduces Retroviral Envelope Abundance and Function and Is Counteracted by glycoGag

ABSTRACT Interferon-induced transmembrane (IFITM) proteins are encoded by many vertebrate species and exhibit antiviral activities against a wide range of viruses. IFITM3, when present in virus-producing cells, reduces the fusion potential of HIV-1 virions, but the mechanism is poorly understood. To...

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Bibliographic Details
Main Authors: Yadvinder S. Ahi, Diborah Yimer, Guoli Shi, Saliha Majdoul, Kazi Rahman, Alan Rein, Alex A. Compton
Format: article
Language:EN
Published: American Society for Microbiology 2020
Subjects:
Env
Online Access:https://doaj.org/article/6c0f7bd7082f450ba1ac4916471050db
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